tetracycline – tetracycline

WID tetracycline View in model
Name tetracycline View in model
Cross references ChEBI: 27902, PubChem: 46506693, CAS: 60-54-8, KEGG: C06570
Type antibiotic_tetracycline View in model
Empirical formula (pH 7.5) H24C22N2O8
SMILES (pH 7.5) [H][C@@]12C[C@@]3([H])C(C(=O)C4=C(O)C=CC=C4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 444.43 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 308.70
Comments Inhibits 30S ribosomal subunit and prevents amino-acyl tRNA from binding to the A site fo the ribosome [PUB_0847].
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

Created 2012-10-01 15:07:08
Last updated 2012-10-01 15:12:33