tetracycline – tetracycline

Name
WID tetracycline View in model
Name tetracycline View in model
Cross references ChEBI: 27902, PubChem: 46506693, CAS: 60-54-8, KEGG: C06570
 
Classification
Type antibiotic_tetracycline View in model
 
Structure
Empirical formula (pH 7.5) H24C22N2O8
SMILES (pH 7.5) [H][C@@]12C[C@@]3([H])C(C(=O)C4=C(O)C=CC=C4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 444.43 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 308.70
 
Comments
Comments Inhibits 30S ribosomal subunit and prevents amino-acyl tRNA from binding to the A site fo the ribosome [PUB_0847].
References

  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682
 
Metadata
Created 2012-10-01 15:07:08
Last updated 2012-10-01 15:12:33