streptomycin – streptomycin

WID streptomycin View in model
Name streptomycin View in model
Cross references ChEBI: 17076, PubChem: 46506845, CAS: 57-92-1, KEGG: C00413
Type antibiotic_aminoglycoside View in model
Empirical formula (pH 7.5) H39C21N7O12
SMILES (pH 7.5) CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]2NC(N)=N)O[C@@H](C)[C@]1(O)C=O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 581.57 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 282.90
Comments Irreversibly binds 30S ribosomal subunit and 16S rRNA. Interferes with decoding site and initiation leading to mRNA misreading [PUB_0847].
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

Created 2012-10-01 15:07:07
Last updated 2012-10-01 15:12:32