sparfloxacin – sparfloxacin

Name
WID sparfloxacin View in model
Name sparfloxacin View in model
Cross references CAS: 110871-86-8, PubChem: 46506453, ChEBI: 9212, KEGG: C07662
 
Classification
Type antibiotic_fluoroquinolone View in model
 
Structure
Empirical formula (pH 7.5) H22C19N4O3F2
SMILES (pH 7.5) C[C@H]1CN(C[C@@H](C)N1)C1=C(F)C2=C(C(=O)C(=CN2C2CC2)C(O)=O)C(N)=C1F
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 392.40 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 734.00
 
Comments
Comments Inhibits topoisomerase II/DNA gyrase and topoisomerase IV [PUB_0847].
References

  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682
 
Metadata
Created 2012-10-01 15:07:07
Last updated 2012-10-01 15:12:32