oxo8dA – 8-hydroxy-2'-deoxyadenosine

Name
WID oxo8dA View in model
Name 8-hydroxy-2'-deoxyadenosine View in model
Traditional name 6-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one
IUPAC name 6-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8,9-dihydro-7H-purin-8-one
Cross references CAS: 62471-63-0, PubChem: 78413756
 
Classification
Type modified_deoxyribonucleoside View in model
 
Structure
Empirical formula (pH 7.5) H13C10N5O4
SMILES (pH 7.5) C1C(C(OC1N2C3=C(C(=NC=N3)N)NC2=O)CO)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 267.24 View in model
van der Waals volume 
(pH 7.5; Å3 molecule‑1)		 215.02
pI 7.06
logP -1.26
logD (pH 7.5) -1.26
 
Function
Reaction participant View in model
 
Comments
Comments 103-320 per 10^7 bases [PUB_0479];
References

  1. Guetens G, De Boeck G, Highley M, van Oosterom AT, de Bruijn EA. Oxidative DNA damage: biological significance and methods of analysis. Crit Rev Clin Lab Sci 39, 331-457 (2002). WholeCell: PUB_0479, PubMed: 12385502
 
Metadata
Created 2012-10-01 15:07:05
Last updated 2012-10-01 15:12:26