n2dA – 2-amino-2'-deoxyadenosine

Name
WID n2dA View in model
Name 2-amino-2'-deoxyadenosine View in model
Traditional name 5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
IUPAC name 5-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Cross references ChEBI: 210129, PubChem: 85408687
 
Classification
Type modified_deoxyribonucleoside View in model
 
Structure
Empirical formula (pH 7.5) H14C10N6O3
SMILES (pH 7.5) C1C(C(OC1N2C=NC3=C2N=C(N=C3N)N)CO)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 266.26 View in model
van der Waals volume 
(pH 7.5; Å3 molecule‑1)		 218.34
pI 10.00
logP -1.34
logD (pH 7.5) -1.38
 
Function
Reaction participant View in model
 
Comments
Comments occurs in bacteriophage DNA [PUB_0477]; 100% adenosine replacement in phage S-2L [PUB_0478];
References

  1. Gommers-Ampt JH, Borst P. Hypermodified bases in DNA. FASEB J 9, 1034-42 (1995). WholeCell: PUB_0478, PubMed: 7649402

  2. Warren RA. Modified bases in bacteriophage DNAs. Annu Rev Microbiol 34, 137-58 (1980). WholeCell: PUB_0477, PubMed: 7002022
 
Metadata
Created 2012-10-01 15:07:04
Last updated 2012-10-01 15:12:23