m7GN – 7-methylguanine

Name
WID	m7GN
Name	7-methylguanine
Traditional name	2-amino-7-methyl-6-oxo-3,9-dihydropurin-7-ium
IUPAC name	2-amino-7-methyl-6-oxo-6,9-dihydro-3H-purin-7-ium
Cross references	PubChem: 46168677

Classification
Type	modified_nucleobase_methylation

Structure
Empirical formula (pH 7.5)	H₈C₆N₅O₁
SMILES (pH 7.5)	C[N+]1=CNC2=C1C(=O)N=C(N)N2
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	166.16
van der Waals volume (pH 7.5; Å³ molecule^‑1)	134.34
pI	6.06
logP	-4.64
logD (pH 7.5)	-5.61

Function
Reaction participant	DNA base methylation (guanine ==> 7-methylguanine; N-methyl-N'-nitro-N-nitrosoguanidine) [c]: GN + H + MNNG ⇒ m7GN + NNG DNA base methylation (guanine ==> 7-methylguanine; N-methyl-N-nitrosourea) [c]: GN + H + MNU ⇒ m7GN + NU DNA base methylation (guanine ==> 7-methylguanine; dimethyl sulfate) [c]: GN + H + MMSO4 ⇒ m7GN + MSO4 DNA base methylation (guanine ==> 7-methylguanine; methyl methanesulphonate) [c]: GN + H + MMS ⇒ m7GN + MS

Metadata
Created	2012-10-01 15:07:03
Last updated	2012-10-01 15:12:21