m3CSN – 3-methylcytosine

Name
WID	m3CSN
Name	3-methylcytosine
Traditional name	4-(methylamino)-1H-pyrimidin-2-one
IUPAC name	4-(methylamino)-1,2-dihydropyrimidin-2-one
Cross references	PubChem: 24505895, CAS: 6220-47-9

Classification
Type	modified_nucleobase_methylation

Structure
Empirical formula (pH 7.5)	H₇C₅N₃O₁
SMILES (pH 7.5)	CNC1=NC(=O)NC=C1
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	125.13
van der Waals volume (pH 7.5; Å³ molecule^‑1)	109.54
pI	12.49
logP	-0.960
logD (pH 7.5)	-0.960

Function
Reaction participant	DNA base methylation (cytosine ==> 3-methylcytosine; dimethyl sulfate) [c]: CSN + MMSO4 ⇒ m3CSN + MSO4 DNA base methylation (cytosine ==> 3-methylcytosine; methyl methanesulphonate) [c]: CSN + MMS ⇒ m3CSN + MS DNA base methylation (cytosine ==> 3-methylcytosine; N-methyl-N-nitrosourea) [c]: CSN + MNU ⇒ m3CSN + NU DNA radiation (gamma-ray) induced base oxidation (3-methylcytosine ==> 3'-hydroxymethylcytosine; hydroxyl radical) gamma_radiation[e] + hydroxyl_radical[c] + m3CSN[c] ⇒ H[c] + hm3CSN[c] DNA base methylation (cytosine ==> 3-methylcytosine; N-methyl-N'-nitro-N-nitrosoguanidine) [c]: CSN + MNNG ⇒ m3CSN + NNG

Metadata
Created	2012-10-01 15:07:02
Last updated	2012-10-01 15:12:19