m1AD – 1-methyladenine

Name
WID	m1AD
Name	1-methyladenine
Traditional name	6-amino-1-methyl-9H-purin-1-ium
IUPAC name	6-amino-1-methyl-9H-purin-1-ium
Cross references	ChEBI: 318410, PubChem: 85510505

Classification
Type	modified_nucleobase_methylation

Structure
Empirical formula (pH 7.5)	H₈C₆N₅
SMILES (pH 7.5)	C[N+]1=C(N)C2=C(NC=N2)N=C1
Charge (pH 7.5)	1
Is hydrophobic	False
Molecular weight (Da)	150.16
van der Waals volume (pH 7.5; Å³ molecule^‑1)	127.05
pI	6.62
logP	-5.47
logD (pH 7.5)	-5.47

Function
Reaction participant	DNA base methylation (adenine ==> 1-methyladenine; N-methyl-N'-nitro-N-nitrosoguanidine) [c]: AD + H + MNNG ⇒ m1AD + NNG DNA base methylation (adenine ==> 1-methyladenine; dimethyl sulfate) [c]: AD + H + MMSO4 ⇒ m1AD + MSO4 DNA base methylation (adenine ==> 1-methyladenine; methyl methanesulphonate) [c]: AD + H + MMS ⇒ m1AD + MS DNA base methylation (adenine ==> 1-methyladenine; N-methyl-N-nitrosourea) [c]: AD + H + MNU ⇒ m1AD + NU

Metadata
Created	2012-10-01 15:07:01
Last updated	2012-10-01 15:12:18