hm5dC – 5'-hydroxymethyl-2'-deoxycytidine
Name | ||
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WID | hm5dC |
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Name | 5'-hydroxymethyl-2'-deoxycytidine |
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Traditional name | 4-amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidin-2-one | |
IUPAC name | 4-amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)-1,2-dihydropyrimidin-2-one | |
Cross references | PubChem: 10256919, CAS: 7226-77-9 | |
Classification | ||
Type | modified_deoxyribonucleoside |
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Structure | ||
Empirical formula (pH 7.5) | H15C10N3O5 | |
SMILES (pH 7.5) | C(C1=CN(C(=O)N=C1N)C2CC(C(O2)CO)O)O | |
Charge (pH 7.5) | 0 | |
Is hydrophobic | False |
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Molecular weight (Da) | 257.24 |
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van der Waals volume (pH 7.5; Å3 molecule‑1) |
218.01 | |
pI | 6.57 | |
logP | -2.78 | |
logD (pH 7.5) | -2.78 | |
Function | ||
Reaction participant |
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Comments | ||
Comments | occurs in bacteriophage DNA [PUB_0477]; majority of m5dC in bacteria is due to action of restriction-modification systems [PUB_0478]; 100% replacement cytidine in E. coli phages T2, T4, T6 [PUB_0478]; hypermodification renders bacteriophage DNA resistant to several restriction endonucleases [PUB_078] | |
References | ||
Metadata | ||
Created | 2012-10-01 15:07:00 | |
Last updated | 2012-10-01 15:12:15 |