hm3CSN – 3'-hydroxymethylcytosine
| Name | ||
|---|---|---|
| WID | hm3CSN |
|
| Name | 3'-hydroxymethylcytosine |
|
| Traditional name | 4-[(hydroxymethyl)amino]-1H-pyrimidin-2-one | |
| IUPAC name | 4-[(hydroxymethyl)amino]-1,2-dihydropyrimidin-2-one | |
| Cross references | PubChem: 91848467 | |
| Classification | ||
| Type | modified_nucleobase |
|
| Structure | ||
| Empirical formula (pH 7.5) | H7C5N3O2 | |
| SMILES (pH 7.5) | C(NC1=NC(=O)NC=C1)O | |
| Charge (pH 7.5) | 0 | |
| Is hydrophobic | False |
|
| Molecular weight (Da) | 141.13 |
|
| van der Waals volume (pH 7.5; Å3 molecule‑1) |
118.12 | |
| pI | 12.16 | |
| logP | -1.54 | |
| logD (pH 7.5) | -1.54 | |
| Function | ||
| Reaction participant | DNA radiation (gamma-ray) induced base oxidation (3-methylcytosine ==> 3'-hydroxymethylcytosine; hydroxyl radical) gamma_radiation[e] + hydroxyl_radical[c] + m3CSN[c] ⇒ H[c] + hm3CSN[c] |
|
| Metadata | ||
| Created | 2012-10-01 15:07:00 | |
| Last updated | 2012-10-01 15:12:15 | |
