gentamicin – gentamicin

Name
WID gentamicin View in model
Name gentamicin View in model
Cross references CAS: 1403-66-3, ChEBI: 17833, PubChem: 46506523, KEGG: C00505
 
Classification
Type antibiotic_aminoglycoside View in model
 
Structure
Empirical formula (pH 7.5) H43C21N5O7
SMILES (pH 7.5) CNC(C)C1CCC(N)C(OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O)O1
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 477.59 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 0.0
 
Comments
Comments Binds 16S rRNA and ribosomal protein S12, and interferes with decoding [PUB_0847].
References

  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682
 
Metadata
Created 2012-10-01 15:06:58
Last updated 2012-10-01 15:12:11