erythromycin – erythromycin

WID erythromycin View in model
Name erythromycin View in model
Cross references CAS: 114-07-8, PubChem: 46508487, ChEBI: 48923, KEGG: C01912
Type antibiotic_macrolide View in model
Empirical formula (pH 7.5) H67C37N1O13
SMILES (pH 7.5) CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 733.92 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 1365.60
Comments Binds 50 S ribosomal subunit near the P site so that binding of tRNA to the donor site is blocked [PUB_0847]. Also prevents translocation of peptides from the A to P site [PUB_0847].
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

Created 2012-10-01 15:06:57
Last updated 2012-10-01 15:12:08