dGpdGp – dGp-dGp

Name
WID	dGpdGp
Name	dGp-dGp
Traditional name	[5-(2-amino-6-oxo-1H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] [5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate
IUPAC name	[5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] [5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate

Classification
Type	dideoxynucleotide

Structure
Empirical formula (pH 7.5)	H₂₃C₂₀N₁₀O₁₃P₂
SMILES (pH 7.5)	NC1=NC2=C(N=CN2C2CC(O)C(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)N3C=NC4=C3N=C(N)NC4=O)O2)C(=O)N1
Charge (pH 7.5)	-3
Is hydrophobic	False
Molecular weight (Da)	673.40
van der Waals volume (pH 7.5; Å³ molecule^‑1)	493.52
pI	1.43
logP	-4.15
logD (pH 7.5)	-8.68

Function
Reaction participant	DNA polymerization (dGTP) [c]: DGMP + DGTP ⇒ dGpdGp + PPI DNA internalization (dGpdGp) (2) dGpdGp[e] + H2O[e] ⇒ (2) DGMP[e] + dGpdGp[c] + H[e] deoxyribonuclease (dGMP) [c]: dGpdGp + H2O ⇒ (2) DGMP + H DNA resection (dGMP) [c]: dGpdGp + H2O ⇒ (2) DGMP + H DNA polymerization (dGTP) [c]: DGMP + DGTP ⇒ dGpdGp + PPI DNA cleavage (dGMP) [c]: dGpdGp + H2O ⇒ (2) DGMP + H

Metadata
Created	2012-10-01 15:06:54
Last updated	2012-10-01 15:12:02