dApdAp – dAp-dAp

Name
WID	dApdAp
Name	dAp-dAp
Traditional name	[5-(6-aminopurin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] [5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate
IUPAC name	[5-(6-amino-9H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] [5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate

Classification
Type	dideoxynucleotide

Structure
Empirical formula (pH 7.5)	H₂₃C₂₀N₁₀O₁₁P₂
SMILES (pH 7.5)	NC1=NC=NC2=C1N=CN2C1CC(O)C(COP([O-])(=O)OC2CC(OC2COP([O-])([O-])=O)N2C=NC3=C2N=CN=C3N)O1
Charge (pH 7.5)	-3
Is hydrophobic	False
Molecular weight (Da)	641.40
van der Waals volume (pH 7.5; Å³ molecule^‑1)	479.41
pI	3.87
logP	-7.44
logD (pH 7.5)	-7.47

Function
Reaction participant	DNA internalization (dApdAp) (2) dApdAp[e] + H2O[e] ⇒ (2) DAMP[e] + dApdAp[c] + H[e] DNA polymerization (dATP) [c]: DAMP + DATP ⇒ dApdAp + PPI DNA cleavage (dAMP) [c]: dApdAp + H2O ⇒ (2) DAMP + H deoxyribonuclease (dAMP) [c]: dApdAp + H2O ⇒ (2) DAMP + H DNA polymerization (dATP) [c]: DAMP + DATP ⇒ dApdAp + PPI DNA resection (dAMP) [c]: dApdAp + H2O ⇒ (2) DAMP + H

Metadata
Created	2012-10-01 15:06:53
Last updated	2012-10-01 15:12:01