Upp – uracil phosphoribosyltransferase
| Name | ||
|---|---|---|
| WID | Upp |
|
| Name | uracil phosphoribosyltransferase |
|
| Cross references | EC: 2.4.2.9, KEGG: R00966, BiGG: UPPRT, BioCyc: URACIL-PRIBOSYLTRANS-RXN | |
| Classification | ||
| Type | chemical |
|
| Reaction | ||
| Stoichiometry | [c]: PRPP + URA ⇒ PPI + UMP |
|
| Catalysis | ||
| Enzyme | MG_030_TRIMER [c] |
|
| Optimal pH | 7.4 (dimensionless) |
|
| Optimal temperature | 42.0 (C) |
|
| Energetics | ||
| Is spontaneous (pH 7.5, 25C, I = 0) | False |
|
| ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) | 3.30 | |
| Keq | 0.00416444571279 () |
|
| Kinetics | ||
| Forward kinetics | v = Vmax * [URA] * [PRPP] / (Km1 * Km2 + Km1 * [URA] + Km2 * [PRPP]); Km1 = 50 (nM), Km2 = 2 (nM), Vmax = 0.07 U/mg |
|
| Associations | ||
| Pathways | NUCLEOTIDE_SALVAGE_PWY | |
| Process | Process_Metabolism |
|
| Metadata | ||
| Created | 2012-10-01 15:09:09 | |
| Last updated | 2012-10-01 15:18:17 | |
