Udk1 – uridine kinase (GTP:Uridine)

Name
WID	Udk1
Name	uridine kinase (GTP:Uridine)
Cross references	EC: 2.7.1.48, KEGG: R00968, BiGG: URIK2, BioCyc: URKI-RXN

Classification
Type	chemical

Reaction
Stoichiometry	[c]: GTP + URI ⇒ GDP + H + UMP

Catalysis
Enzyme	MG_382_TETRAMER [c]
Optimal pH	7.2 (dimensionless)
Optimal temperature	40.0 (C)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	-3.80
K_eq	550.954774449 ()

Kinetics
Forward kinetics	v = V_max * [URI] / (K_m + [URI]); K_m = 350 (nM), V_max = 200.0 U/mg (Show evidence) Value: Rate law: VmaxURI/(Km+URI); Km = 0.35 mM, Vmax = 200 umol/(minmg) (None) Measured: Yes Species: Escherichia coli References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	NUCLEOTIDE_SALVAGE_PWY
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:09:09
Last updated	2012-10-01 15:18:16