TpiA – triose-phosphate isomerase

Name
WID	TpiA
Name	triose-phosphate isomerase
Cross references	SABIO-RK: 20971, EC: 5.3.1.1, KEGG: R01015, BiGG: TPI, BioCyc: TRIOSEPISOMERIZATION-RXN

Classification
Type	chemical

Reaction
Stoichiometry	[c]: T3P2 ⇔ T3P1

Catalysis
Enzyme	MG_431_DIMER [c]
Optimal pH	7.9 (dimensionless)
Optimal temperature	43.0 (C)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	1.40
K_eq	0.0977496431257 ()

Kinetics
Forward kinetics	v = V_max * [T3P2] / (K_m + [T3P2]); K_m = 1230 (nM), V_max = 49000.0 1/min (Show evidence) Value: Rate law: VmaxT3P2/(Km+T3P2); Km = 1.23 mM, Vmax = 49000 1/min (None) Measured: Yes* Species: Saccharomyces cerevisiae References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	GLYCOLYSIS
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:09:02
Last updated	2012-10-01 15:17:55