RNACleavage_DeaD_AMP – RNA cleavage (AMP)

Name
WID RNACleavage_DeaD_AMP View in model
Name RNA cleavage (AMP) View in model
 
Reaction
Stoichiometry [c]: ApAp + ATP + (2) H2O ⇒ ADP + (2) AMP + (2) H + PI View in model
 
Catalysis
Enzyme MG_425_DIMER [c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
 
Kinetics
Forward kinetics Vmax = 88.8 1/min View in model
 
Associations
Process Process_RNAProcessing View in model
 
Comments
Comments Reaction requires on average 2.37 ATP (210 ATP/min [PUB_0069])/(1.48 rxn/s [PUB_0688]). Reaction catalyzed at rate 1.48 1/s [PUB_0688].
References

  1. Cordin O, Banroques J, Tanner NK, Linder P. The DEAD-box protein family of RNA helicases. Gene 367, 17-37 (2006). WholeCell: PUB_0069, PubMed: 16337753

  2. Theissen B, Karow AR, Köhler J, Gubaev A, Klostermeier D. Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase. Proc Natl Acad Sci U S A 105, 548-53 (2008). WholeCell: PUB_0688, PubMed: 18184816
 
Metadata
Created 2012-10-01 15:09:00
Last updated 2012-10-01 15:17:48