PhePhe – L-phenylalanyl-L-phenylalanine

Name
WID	PhePhe
Name	L-phenylalanyl-L-phenylalanine
Traditional name	phe-phe
IUPAC name	2-(2-amino-3-phenylpropanamido)-3-phenylpropanoic acid
Cross references	PubChem: 8189514

Classification
Type	dipeptide

Structure
Empirical formula (pH 7.5)	H₂₀C₁₈N₂O₃
SMILES (pH 7.5)	C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)O)N
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	312.36
van der Waals volume (pH 7.5; Å³ molecule^‑1)	291.13
pI	6.04
logP	-0.500
logD (pH 7.5)	-0.550

Concentrations
Media composition (SP4; mM)	3.40

Function
Reaction participant	Protein degradation (PHE) [c]: ATP + (2) H2O + PhePhe ⇒ ADP + H + (2) PHE + PI Protein polymerization (Phe) [c]: (2) PHE ⇒ H2O + PhePhe Dipeptide import (Phe-Phe) [c]: H2O + PhePhe ⇒ (2) PHE Protein degradation (PHE) [c]: ATP + (2) H2O + PhePhe ⇒ ADP + H + (2) PHE + PI oligopeptide (Phe) transport via ABC system ATP[c] + H2O[c] + PhePhe[e] ⇒ ADP[c] + H[c] + PhePhe[c] + PI[c]

Metadata
Created	2012-10-01 15:07:06
Last updated	2012-10-01 15:12:28