Pgi – glucose-6-phosphate isomerase

Name
WID	Pgi
Name	glucose-6-phosphate isomerase
Cross references	SABIO-RK: 16087, EC: 5.3.1.9, BiGG: PGI, BioCyc: PGLUCISOM-RXN, KEGG: R00771

Classification
Type	chemical

Reaction
Stoichiometry	[c]: G6P ⇔ F6P

Catalysis
Enzyme	MG_111_DIMER [c]
Optimal pH	7.7 (dimensionless)
Optimal temperature	76.0 (C)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	-0.800
K_eq	3.77639190606 ()

Kinetics
Forward kinetics	v = V_max * [G6P] / (K_m + [G6P]); K_m = 11 (nM), V_max = 740.0 U/mg (Show evidence) Value: Rate law: VmaxG6P/(Km+G6P); Km = 11 uM, Vmax = 740 U/mg (None) Measured: Yes* Species: Lactobacillus casei References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	GLYCOLYSIS
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:08:55
Last updated	2012-10-01 15:17:32