Pdp2 – thymidine phosphorylase

Name
WID	Pdp2
Name	thymidine phosphorylase
Cross references	SABIO-RK: 19642, EC: 2.4.2.3, KEGG: R01570, BioCyc: THYM-PHOSPH-RXN, BiGG: TMDPP

Classification
Type	chemical

Reaction
Stoichiometry	[c]: DT + PI ⇔ DR1P + THY

Catalysis
Enzyme	MG_051_DIMER [c]
Optimal pH	7.4 (dimensionless)
Optimal temperature	51.0 (C)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	2.00
K_eq	0.0360833936403 ()

Kinetics
Forward kinetics	v = V_max * [DT] / (K_m + [DT]); K_m = 152 (nM), V_max = 0.001468 U/mg (Show evidence) Value: Rate law: VmaxDT/(Km+DT); Km = 152 uM, Vmax = 1468 pmol/(minmg) (None) Measured: Yes Species: Mus musculus References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	NUCLEOTIDE_SALVAGE_PWY
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:08:53
Last updated	2012-10-01 15:17:28