PI – phosphate

Name
WID	PI
Name	phosphate
Traditional name	hydrogen phosphate
IUPAC name	hydrogen phosphate
Cross references	ChEBI: 18367, PDBCCD: 2HP, PubChem: 3311, CAS: 7664-38-2, ThreeDMET: B00002, ... 4 more

Classification
Type	ion

Structure
Empirical formula (pH 7.5)	H₁O₄P₁
SMILES (pH 7.5)	OP([O-])([O-])=O
Charge (pH 7.5)	-2
Is hydrophobic	False
Molecular weight (Da)	95.98
van der Waals volume (pH 7.5; Å³ molecule^‑1)	59.39
Δ_fG^'o (pH 7.5, 25C, I = 0; kJ mol^‑1)	-1055.40
logP	-1.02
logD (pH 7.5)	-3.84

Concentrations
Biomass composition (SP4 media, 5% CO₂, 37C; mmol gDCW^‑1)	0.00369753 [c]
Media composition (SP4; mM)	1.50

Function
Complex subunit	cell division protein ftsZ deactivated 9mer [c]: (9) H2O + MG_224_9MER_GTP ⇒ (9) H + (9) PI + MG_224_9MER_GDP
Reaction participant	Protein degradation (ALA) [c]: AlaAla + ATP + (2) H2O ⇒ ADP + (2) ALA + H + PI FtsZ deactivation [c]: H2O + MG_224_MONOMER_GTP ⇔ H + MG_224_MONOMER_GDP + PI purine-nucleoside phosphorylase (Deoxyguanosine) [c]: DG + PI ⇔ DR1P + GN Protein degradation (PHE) [c]: ATP + (2) H2O + PhePhe ⇒ ADP + H + (2) PHE + PI Protein degradation (GLU) [c]: ATP + GluGlu + (2) H2O ⇒ ADP + (2) GLU + H + PI ... 254 more 5'-nucleotidase (2'-deoxythymidine monophosphate-[6,4]-2'-deoxythymidine monophosphate) [c]: dTMP64dTMP + (2) H2O ⇒ dT64dT + (2) PI 5'-nucleotidase (2'-deoxythymidine monophosphate glycol) [c]: dTMP_GLYC + H2O ⇒ dT_GLYC + PI Chromosome condensation [c]: ATP + H2O + MG_213_214_298_6MER ⇒ H + MG_213_214_298_6MER_ADP + PI RNA cleavage (CMP) [c]: CpCp + GTP + (2) H2O ⇒ (2) CMP + GDP + (2) H + PI pyrimidine-nucleoside phosphorylase (uracil) [c]: (2) H + PI + URI ⇔ R1P + URA Mannose-6-phosphate transport via phosphate antiport MAN6P[e] + (2) PI[c] ⇒ MAN6P[c] + (2) PI[e] Protein degradation (SER) [c]: ATP + (2) H2O + SerSer ⇒ ADP + H + PI + (2) SER 5'-nucleotidase (2-'deoxycytidine monophosphate glycol) [c]: dCMP_GLYC + H2O ⇒ dC_GLYC + PI RNA cleavage (AMP) [c]: ApAp + ATP + (2) H2O ⇒ ADP + (2) AMP + (2) H + PI 5'-nucleotidase (3,N4-etheno-2'-deoxycytidine monophosphate) [c]: epsilon3N4dCMP + H2O ⇒ epsilon3N4dC + PI RNA cleavage (AMP) [c]: ApAp + GTP + (2) H2O ⇒ (2) AMP + GDP + (2) H + PI iron (II) transporting ATPase ATP[c] + FE2[e] + H2O[c] ⇒ ADP[c] + FE2[c] + H[c] + PI[c] 5'-nucleotidase (dTMP) [c]: DTMP + H2O ⇒ DT + PI ornithine carbamoyltransferase [c]: CAP + ORN ⇔ CITR + H + PI 3',5'-bisphosphate nucleotidase [c]: H2O + PAP ⇒ AMP + PI Chromosome segregation (CobQ) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (1-ethyl-2'-deoxyadenosine monophosphate) [c]: e1dAMP + H2O ⇒ e1dA + PI oligopeptide (Gln) transport via ABC system ATP[c] + GlnGln[e] + H2O[c] ⇒ ADP[c] + GlnGln[c] + H[c] + PI[c] Ribosome assembly (EngA) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (m1GMP) [c]: H2O + m1GMP ⇒ m1G + PI 5'-nucleotidase (5,6-dihydro-2'-deoxythymidine monophosphate) [c]: DHdTMP + H2O ⇒ DHdT + PI 5'-nucleotidase (s2UMP) [c]: H2O + s2UMP ⇒ PI + s2U purine-nucleoside phosphorylase (Deoxyuridine) [c]: DU + PI ⇔ DR1P + URA phosphotransacetylase [c]: ACCOA + PI ⇔ ACTP + COA DnaA inactivation [c]: H2O + MG_469_1MER_ATP ⇒ H + MG_469_1MER_ADP + PI Chromosome segregation (MraZ) [c]: GTP + H2O ⇒ GDP + H + PI phosphoenolpyruvate carboxylase [c]: CO2 + H2O + PEP ⇒ H + OA + PI 5'-nucleotidase (5-methyl-2'-deoxycytidine monophosphate) [c]: H2O + m5dCMP ⇒ m5dC + PI RNA cleavage (UMP) [c]: ATP + (2) H2O + UpUp ⇒ ADP + (2) H + PI + (2) UMP Protein degradation (THR) [c]: ATP + (2) H2O + ThrThr ⇒ ADP + H + PI + (2) THR 5'-nucleotidase (2'-deoxycytidine monophosphate-[6,4]-2'-deoxythymidine monophosphate dewar product) [c]: dCMP64dTMP_dewar + (2) H2O ⇒ dC64dT_dewar + (2) PI 5'-nucleotidase (3-ethyl-2'-deoxyadenosine monophosphate) [c]: e3dAMP + H2O ⇒ e3dA + PI 5'-nucleotidase (cmnm5s2UMP) [c]: cmnm5s2UMP + H2O ⇒ cmnm5s2U + PI oligopeptide (Tyr) transport via ABC system ATP[c] + H2O[c] + TyrTyr[e] ⇒ ADP[c] + H[c] + PI[c] + TyrTyr[c] phosphoserine phosphatase [c]: H2O + pSER ⇒ PI + SER 5'-nucleotidase (m7GMP) [c]: H2O + m7GMP ⇒ m7G + PI sugar phosphatase (glucose-6-phosphate) [c]: G6P + H2O ⇒ GLC + PI phosphate transport via ABC system ATP[c] + H2O[c] + PI[e] ⇒ ADP[c] + H[c] + (2) PI[c] Protein degradation (GLY) [c]: ATP + GlyGly + (2) H2O ⇒ ADP + (2) GLY + H + PI Protein degradation (PHE) [c]: ATP + (2) H2O + PhePhe ⇒ ADP + H + (2) PHE + PI alpha-L-glutamate ligase [c]: (4) ATP + (4) GLU + (4) H2O ⇒ (4) ADP + (4) H + (4) H2O + (4) PI purine-nucleoside phosphorylase (Deoxyinosine) [c]: dINS + PI ⇔ DR1P + HYXN 5'-nucleotidase (3-ethyl-2'-deoxyguanosine monophosphate) [c]: e3dGMP + H2O ⇒ e3dG + PI 5'-nucleotidase (1-methyl-2'-deoxyadenosine monophosphate) [c]: H2O + m1dAMP ⇒ m1dA + PI 5'-nucleotidase (GmMP) [c]: GmMP + H2O ⇒ Gm + PI oligopeptide (Cys) transport via ABC system ATP[c] + CysCys[e] + H2O[c] ⇒ ADP[c] + CysCys[c] + H[c] + PI[c] 5'-nucleotidase (6'-O-methyl-2'-deoxyguanosine monophosphate) [c]: H2O + O6mdGMP ⇒ O6mdG + PI sugar phosphatase (sn-glycerol-2-phosphate) [c]: GL2P + H2O ⇒ GL + PI Protein degradation (ALA) [c]: AlaAla + ATP + (2) H2O ⇒ ADP + (2) ALA + H + PI 5'-nucleotidase (1-methyl-2'-deoxyguanosine monophosphate) [c]: H2O + m1dGMP ⇒ m1dG + PI Ribosome assembly (EngB) [c]: GTP + H2O ⇒ GDP + H + PI oligopeptide (Trp) transport via ABC system ATP[c] + H2O[c] + TrpTrp[e] ⇒ ADP[c] + H[c] + PI[c] + TrpTrp[c] cobalt transport via ABC system ATP[c] + CO[e] + H2O[c] ⇒ ADP[c] + CO[c] + H[c] + PI[c] 5'-nucleotidase (7-methyl-2'-deoxyadenosine monophosphate) [c]: H2O + m7dAMP ⇒ m7dA + PI 5'-nucleotidase (5-hydroxy-6-hydroxy-2'-deoxyuridine monophosphate) [c]: H2O + ho5ho6dUMP ⇒ ho5ho6dU + PI 5'-nucleotidase (N6-(2-Deoxy-α,β-d-erythro-pentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine monophosphate) [c]: FAPydGMP + H2O ⇒ FAPydG + PI 5'-nucleotidase (5-hydroxymethyl-2'-deoxyuridine monophosphate) [c]: H2O + hm5dUMP ⇒ hm5dU + PI Fucose-1-phosphate transport via phosphate antiport FUC1P[e] + (2) PI[c] ⇒ FUC1P[c] + (2) PI[e] 5'-nucleotidase (2'-deoxycytidine monophosphate-[6,4]-2'-deoxycytidine monophosphate dewar product) [c]: dCMP64dCMP_dewar + (2) H2O ⇒ dC64dC_dewar + (2) PI drug efflux (doxorubicin) via ABC system ATP[c] + doxorubicin[c] + H2O[c] ⇒ ADP[c] + doxorubicin[e] + H[c] + PI[c] 5'-nucleotidase (3-ethyl-2'-deoxycytidine monophosphate) [c]: e3dCMP + H2O ⇒ e3dC + PI Protein degradation (ILE) [c]: ATP + (2) H2O + IleIle ⇒ ADP + H + (2) ILE + PI glycerol transport via ABC system ATP[c] + GL[e] + H2O[c] ⇒ ADP[c] + GL[c] + H[c] + PI[c] 5'-nucleotidase (8,5'-cyclo-2'-deoxyadenosine monophosphate) [c]: cyclodAMP + H2O ⇒ cyclodA + PI 5'-nucleotidase (7-ethyl-2'-deoxyadenosine monophosphate) [c]: e7dAMP + H2O ⇒ e7dA + PI 5'-nucleotidase (2'-deoxycytidine monophosphate-[6,4]-2'-deoxythymidine monophosphate) [c]: dCMP64dTMP + (2) H2O ⇒ dC64dT + (2) PI 5'-nucleotidase (m6AMP) [c]: H2O + m6AMP ⇒ m6A + PI 5'-nucleotidase (4'-O-ethyl-2'-deoxythymidine monophosphate) [c]: H2O + O4edTMP ⇒ O4edT + PI 5'-nucleotidase (3'-methyl-2'-deoxythymidine monophosphate) [c]: H2O + m3dTMP ⇒ m3dT + PI sulfate transporting ATPase ATP[c] + H2O[c] + SO4[e] ⇒ ADP[c] + H[c] + PI[c] + SO4[c] Protein degradation (THR) [c]: ATP + (2) H2O + ThrThr ⇒ ADP + H + PI + (2) THR 5'-nucleotidase (6'-O-ethyl-2'-deoxyguanosine monophosphate) [c]: H2O + O6edGMP ⇒ O6edG + PI D-ribose transport via ABC system ATP[c] + H2O[c] + RIB[e] ⇒ ADP[c] + H[c] + PI[c] + RIB[c] Protein degradation (CYS) [c]: ATP + CysCys + (2) H2O ⇒ ADP + (2) CYS + H + PI 5'-nucleotidase (7-(2'-oxoethyl)-2'-deoxyguanosine monophosphate) [c]: H2O + oxoethyl7dGMP ⇒ oxoethyl7dG + PI 5'-nucleotidase (5-ethyl-2'-deoxycytidine monophosphate) [c]: e5dCMP + H2O ⇒ e5dC + PI 5'-nucleotidase (dUMP) [c]: DUMP + H2O ⇒ DU + PI RNA cleavage (GMP) [c]: ATP + GpGp + (2) H2O ⇒ ADP + (2) GMP + (2) H + PI 5'-nucleotidase (2'-deoxy-3'-(5-hydroxyhydantoin)-ribose monophosphate) [c]: H2O + ho5hydantoin_dRiboseMP ⇒ ho5hydantoin_dRibose + PI Protein degradation (MET) [c]: ATP + (2) H2O + MetMet ⇒ ADP + H + (2) MET + PI 5'-nucleotidase (AMP) [c]: AMP + H2O ⇒ ADN + PI 5'-nucleotidase (6-methyl-2'-deoxyadenosine monophosphate) [c]: H2O + m6dAMP ⇒ m6dA + PI 5'-nucleotidase (4-ethyl-2'-deoxycytidine monophosphate) [c]: e4dCMP + H2O ⇒ e4dC + PI DNA unwinding [c]: ATP + H2O ⇒ ADP + H + PI toxin secretion (nisin) via ABC system ATP[c] + H2O[c] + nisin[c] ⇒ ADP[c] + H[c] + nisin[e] + PI[c] formate-tetrahydrofolate ligase [c]: ATP + FOR + THF ⇒ ADP + FTHF10 + PI 5'-nucleotidase (N2,3-etheno-2'-deoxyguanosine monophosphate) [c]: epsilonN23dGMP + H2O ⇒ epsilonN23dG + PI sugar phosphatase (2-deoxy-glucose-6-phosphate) [c]: deoxyG6P + H2O ⇒ deoxyGLC + (2) H + PI Ribosome assembly (Era) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (3'-hydroxymethyl-2'-deoxycytidine monophosphate) [c]: H2O + hm3dCMP ⇒ hm3dC + PI glyceraldehyde-3-phosphate dehydrogenase [c]: NAD + PI + T3P1 ⇔ DPG + H + NADH 5'-nucleotidase (2'-deoxy-3'-(5-hydroxy-5-methyl-hydantoin)-ribose monophosphate) [c]: H2O + hm5hydantoin_dRiboseMP ⇒ hm5hydantoin_dRibose + PI 5'-nucleotidase (IMP) [c]: H2O + IMP ⇒ INS + PI glutamyl-tRNA (MG502) amidotransferase [c]: ATP + GLN + GLU + H2O ⇒ ADP + GLN + GLU + H + PI Ribosome assembly (RbfA) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (3'-ethyl-2'-deoxythymidine monophosphate) [c]: e3dTMP + H2O ⇒ e3dT + PI oligopeptide (Ala) transport via ABC system AlaAla[e] + ATP[c] + H2O[c] ⇒ ADP[c] + AlaAla[c] + H[c] + PI[c] 5'-nucleotidase (5-formyl-2'-deoxyuridine monophosphate) [c]: f5dUMP + H2O ⇒ f5dU + PI Protein degradation (ARG) [c]: ArgArg + ATP + (2) H2O ⇒ ADP + (2) ARG + H + PI methionine adenosyltransferase [c]: ATP + H2O + MET ⇒ AMET + PI + PPI Protein degradation (VAL) [c]: ATP + (2) H2O + ValVal ⇒ ADP + H + PI + (2) VAL glycerol transport via ABC system ATP[c] + GL3P[e] + H2O[c] ⇒ ADP[c] + GL3P[c] + H[c] + PI[c] oligopeptide (Ser) transport via ABC system ATP[c] + H2O[c] + SerSer[e] ⇒ ADP[c] + H[c] + PI[c] + SerSer[c] Protein degradation (LYS) [c]: ATP + (2) H2O + LysLys ⇒ ADP + H + (2) LYS + PI 5'-nucleotidase (7-ethyl-2'-deoxyguanosine monophosphate) [c]: e7dGMP + H2O ⇒ e7dG + PI Protein degradation (GLN) [c]: ATP + GlnGln + (2) H2O ⇒ ADP + (2) GLN + H + PI phosphatidylglycerol phosphate phosphatase (n-C18:1) H2O[c] + PGP181[m] ⇒ PG181[m] + PI[c] 5'-nucleotidase (1,N2-etheno-2'-deoxyguanosine monophosphate) [c]: epsilon1N2dGMP + H2O ⇒ epsilon1N2dG + PI Protein degradation (TRP) [c]: ATP + (2) H2O + TrpTrp ⇒ ADP + H + PI + (2) TRP 5'-nucleotidase (8-ethyl-2'-deoxyguanosine monophosphate) [c]: e8dGMP + H2O ⇒ e8dG + PI 5'-nucleotidase (3-methyl-2'-deoxycytidine monophosphate) [c]: H2O + m3dCMP ⇒ m3dC + PI 5'-nucleotidase (8-Oxo-2'-deoxyguanosine monophosphate; 8-hydroxy-2'-deoxyguanosine monophosphate) [c]: H2O + oxo8dGMP ⇒ oxo8dG + PI Protein degradation (LEU) [c]: ATP + (2) H2O + LeuLeu ⇒ ADP + H + (2) LEU + PI 5'-nucleotidase (2'-deoxyinosine monophosphate) [c]: dINSMP + H2O ⇒ dINS + PI DNA incision [c]: ATP + (2) dRibose5P_dRibose5P + (3) H2O ⇒ ADP + (4) DR5P + (3) H + PI 5'-nucleotidase (2'-deoxythymidine monophosphate-[6,4]-2'-deoxycytidine monophosphate) [c]: dTMP64dCMP + (2) H2O ⇒ dT64dC + (2) PI DNA recombination Holliday junction migration [c]: ATP + H2O ⇒ ADP + H + PI drug efflux (nisin) via ABC system ATP[c] + H2O[c] + nisin[c] ⇒ ADP[c] + H[c] + nisin[e] + PI[c] 5'-nucleotidase (cyclobutane 2'-deoxythymidine monophosphate 2'-deoxycytidine monophosphate) [c]: cyclobutane_dTMPdCMP + (2) H2O ⇒ cyclobutane_dTdC + (2) PI Negative supercoiling (gyrase) [c]: (2) ATP + (2) H2O ⇒ (2) ADP + (2) H + (2) PI purine-nucleoside phosphorylase (Deoxyadenosine) [c]: DA + PI ⇔ AD + DR1P 5'-nucleotidase (8-methyl-2'-deoxyguanosine monophosphate) [c]: H2O + m8dGMP ⇒ m8dG + PI 5'-nucleotidase (5-hydroxy-2'-deoxyuridine monophosphate) [c]: H2O + ho5dUMP ⇒ ho5dU + PI 5'-nucleotidase (dCMP) [c]: DCMP + H2O ⇒ DC + PI 5'-nucleotidase (2'-deoxyxanthosine monophosphate) [c]: dXANMP + H2O ⇒ dXAN + PI Protein degradation (TYR) [c]: ATP + (2) H2O + TyrTyr ⇒ ADP + H + PI + (2) TYR 5'-nucleotidase (3-methyl-2'-deoxyadenosine monophosphate) [c]: H2O + m3dAMP ⇒ m3dA + PI Protein degradation (LEU) [c]: ATP + (2) H2O + LeuLeu ⇒ ADP + H + (2) LEU + PI Protein degradation (ASN) [c]: AsnAsn + ATP + (2) H2O ⇒ ADP + (2) ASN + H + PI 5'-nucleotidase (2'-deoxythymidine monophosphate-[6,4]-2'-deoxycytidine monophosphate dewar product) [c]: dTMP64dCMP_dewar + (2) H2O ⇒ dT64dC_dewar + (2) PI Protein degradation (ASN) [c]: AsnAsn + ATP + (2) H2O ⇒ ADP + (2) ASN + H + PI 5'-nucleotidase (5'-dihydroxypentyl-2'-deoxyuridine monophosphate) [c]: dhpdUMP + H2O ⇒ dhpdU + PI Protein degradation (SER) [c]: ATP + (2) H2O + SerSer ⇒ ADP + H + PI + (2) SER Protein degradation (GLN) [c]: ATP + GlnGln + (2) H2O ⇒ ADP + (2) GLN + H + PI 5'-nucleotidase (cyclobutane 2'-deoxycytidine monophosphate dimer) [c]: cyclobutane_dCMPdCMP + (2) H2O ⇒ cyclobutane_dCdC + (2) PI Protein degradation (LYS) [c]: ATP + (2) H2O + LysLys ⇒ ADP + H + (2) LYS + PI Protein degradation (PRO) [c]: ATP + (2) H2O + ProPro ⇒ ADP + H + PI + (2) PRO Phosphotyrosine phosphatase [c]: H2O + pTYR ⇒ PI + TYR 5'-nucleotidase (beta-D-glucosylhydroxymethyl-2'-deoxycytidine monophosphate) [c]: glchm5dCMP + H2O ⇒ glchm5dC + PI DNA excision [c]: ATP + H2O ⇒ ADP + H + PI Protein translocation (SRP) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (8,5'-cyclo-2'-deoxyguanosine monophosphate) [c]: cyclodGMP + H2O ⇒ cyclodG + PI 5'-nucleotidase (1,N6-etheno-2'-deoxyadenosine monophosphate) [c]: epsilon1N6dAMP + H2O ⇒ epsilon1N6dA + PI Protein degradation (GLU) [c]: ATP + GluGlu + (2) H2O ⇒ ADP + (2) GLU + H + PI Chromosome segregation (Obg) [c]: GTP + H2O ⇒ GDP + H + PI zinc-transporting ATPase ATP[c] + H2O[c] + ZN[e] ⇒ ADP[c] + H[c] + PI[c] + ZN[c] Protein degradation (ILE) [c]: ATP + (2) H2O + IleIle ⇒ ADP + H + (2) ILE + PI 5'-nucleotidase (m62AMP) [c]: H2O + m62AMP ⇒ m62A + PI oligopeptide (Phe) transport via ABC system ATP[c] + H2O[c] + PhePhe[e] ⇒ ADP[c] + H[c] + PhePhe[c] + PI[c] 5'-nucleotidase (beta-D-glucosylhydroxymethyl-2'-deoxyuridine monophosphate) [c]: glchm5dUMP + H2O ⇒ glchm5dU + PI 5'-nucleotidase (2'-O-methyl-2'-deoxycytidine monophosphate) [c]: H2O + O2mdCMP ⇒ O2mdC + PI 5'-nucleotidase (5'-hydroxymethyl-2'-deoxycytidine monophosphate) [c]: H2O + hm5dCMP ⇒ hm5dC + PI oligopeptide (Met) transport via ABC system ATP[c] + H2O[c] + MetMet[e] ⇒ ADP[c] + H[c] + MetMet[c] + PI[c] spermidine transport via ABC system ATP[c] + H2O[c] + SPMD[e] ⇒ ADP[c] + H[c] + PI[c] + SPMD[c] 5'-nucleotidase (2'-deoxythymidine monophosphate-[6,4]-2'-deoxythymidine monophosphate dewar product) [c]: dTMP64dTMP_dewar + (2) H2O ⇒ dT64dT_dewar + (2) PI oligopeptide (Thr) transport via ABC system ATP[c] + H2O[c] + ThrThr[e] ⇒ ADP[c] + H[c] + PI[c] + ThrThr[c] sugar phosphatase (mannose-6-phosphate) [c]: H2O + MAN6P ⇒ MAN + PI oligopeptide (Glu) transport via ABC system ATP[c] + GluGlu[e] + H2O[c] ⇒ ADP[c] + GluGlu[c] + H[c] + PI[c] Protein degradation (PRO) [c]: ATP + (2) H2O + ProPro ⇒ ADP + H + PI + (2) PRO 5'-nucleotidase (4-methyl-2'-deoxycytidine monophosphate) [c]: H2O + m4dCMP ⇒ m4dC + PI methylenetetrahydrofolate cyclohydrase [c]: ATP + FTHF10 + (3) H ⇔ ADP + METTHF + PI Protein degradation (CYS) [c]: ATP + CysCys + (2) H2O ⇒ ADP + (2) CYS + H + PI 5'-nucleotidase (4'-O-methyl-2'-deoxythymidine monophosphate) [c]: H2O + O4mdTMP ⇒ O4mdT + PI phosphatidylglycerol phosphate phosphatase (n-C16:0) H2O[c] + PGP160[m] ⇒ PG160[m] + PI[c] Phosphonoacetaldehyde hydrolase [c]: H2O + PPAA ⇒ ACAL + (2) H + PI Protein degradation (TYR) [c]: ATP + (2) H2O + TyrTyr ⇒ ADP + H + PI + (2) TYR RNA cleavage (CMP) [c]: ATP + CpCp + (2) H2O ⇒ ADP + (2) CMP + (2) H + PI sugar phosphatase (sn-glycerol-1-phosphate) [c]: H2O + SNGLYP ⇒ GL + PI 5'-nucleotidase (8-hydroxy-2'-deoxyadenosine monophosphate) [c]: H2O + oxo8dAMP ⇒ oxo8dA + PI oligopeptide (Asn) transport via ABC system AsnAsn[e] + ATP[c] + H2O[c] ⇒ ADP[c] + AsnAsn[c] + H[c] + PI[c] sugar phosphatase (sorbitol-6-phosphate) [c]: H2O + SBT6P ⇒ H + PI + SBT Protein degradation (ASP) [c]: AspAsp + ATP + (2) H2O ⇒ ADP + (2) ASP + H + PI oligopeptide (Ile) transport via ABC system ATP[c] + H2O[c] + IleIle[e] ⇒ ADP[c] + H[c] + IleIle[c] + PI[c] EcoD DNA restriction/modification, DNA restriction [c]: ATP + (2) dRibose5P_dRibose5P + (3) H2O ⇒ ADP + (4) DR5P + (3) H + PI 5'-nucleotidase (2'-O-ethyl-2'-deoxythymidine monophosphate) [c]: H2O + O2edTMP ⇒ O2edT + PI Chromosome segregation (Era) [c]: GTP + H2O ⇒ GDP + H + PI ATP synthase (four protons for one ATP) (periplasm) ADP[c] + (4) H[e] + H[c] + PI[c] ⇔ ATP[c] + (4) H[c] + H2O[c] 5'-nucleotidase (2'-O-ethyl-2'-deoxycytidine monophosphate) [c]: H2O + O2edCMP ⇒ O2edC + PI Glucose-6-phosphate transport via phosphate antiport G6P[e] + (2) PI[c] ⇒ G6P[c] + (2) PI[e] 5'-nucleotidase (m2GMP) [c]: H2O + m2GMP ⇒ m2G + PI oligopeptide (Arg) transport via ABC system ArgArg[e] + ATP[c] + H2O[c] ⇒ ADP[c] + ArgArg[c] + H[c] + PI[c] sugar phosphatase (ribose-5-phosphate) [c]: H2O + R5P ⇒ PI + RIB 5'-nucleotidase (N6-carbamoylmethyl-2'-deoxyadenosine monophosphate) [c]: carbamoylmethyl6dAMP + H2O ⇒ carbamoylmethyl6dA + PI 5'-nucleotidase (6-aza-2'-deoxythymidine monophosphate) [c]: aza6dTMP + H2O ⇒ aza6dT + PI phosphothreonine phosphatase [c]: H2O + pTHR ⇒ PI + THR Ribosome assembly (Obg) [c]: GTP + H2O ⇒ GDP + H + PI 5'-nucleotidase (GMP) [c]: GMP + H2O ⇒ GSN + PI Protein degradation (HIS) [c]: ATP + (2) H2O + HisHis ⇒ ADP + H + (2) HIS + PI 5'-nucleotidase (5,6-dihydroxy-2'-deoxyuridine monophosphate) [c]: DHdUMP + H2O ⇒ DHdU + PI 5'-nucleotidase (2-amino-2'-deoxyadenosine monophosphate) [c]: H2O + n2dAMP ⇒ n2dA + PI RNA cleavage (GMP) [c]: GpGp + GTP + (2) H2O ⇒ GDP + (2) GMP + (2) H + PI Protein translocation (SecA) [c]: ATP + H2O ⇒ ADP + H + PI Protein degradation (GLY) [c]: ATP + GlyGly + (2) H2O ⇒ ADP + (2) GLY + H + PI 5'-nucleotidase (m5CMP) [c]: H2O + m5CMP ⇒ m5C + PI phosphatidylglycerol phosphate phosphatase (n-C16:1) H2O[c] + PGP161[m] ⇒ PG161[m] + PI[c] purine-nucleoside phosphorylase (Inosine) [c]: HYXN + R1P ⇔ (2) H + INS + PI 5'-nucleotidase (2'-O-methyl-2'-deoxythymidine monophosphate) [c]: H2O + O2mdTMP ⇒ O2mdT + PI purine-nucleoside phosphorylase (Xanthosine) [c]: R1P + XAN ⇔ (2) H + PI + XTSN 5'-nucleotidase (8-aza-2'-deoxyadenosine monophosphate) [c]: aza8dAMP + H2O ⇒ aza8dA + PI Protein degradation (VAL) [c]: ATP + (2) H2O + ValVal ⇒ ADP + H + PI + (2) VAL purine-nucleoside phosphorylase (Guanosine) [c]: GN + R1P ⇔ GSN + (2) H + PI 5'-nucleotidase (cyclobutane 2'-deoxycytidine monophosphate 2'-deoxythymidine monophosphate) [c]: cyclobutane_dCMPdTMP + (2) H2O ⇒ cyclobutane_dCdT + (2) PI molybdate transporting ATPase ATP[c] + H2O[c] + MOBD[e] ⇒ ADP[c] + H[c] + MOBD[c] + PI[c] oligopeptide (Asp) transport via ABC system AspAsp[e] + ATP[c] + H2O[c] ⇒ ADP[c] + AspAsp[c] + H[c] + PI[c] 5'-nucleotidase (cyclobutane 2'-deoxythymidine monophosphate dimer) [c]: cyclobutane_dTMPdTMP + (2) H2O ⇒ cyclobutane_dTdT + (2) PI Magnesium-transporting ATPase ATP[c] + H2O[c] + MG[e] ⇒ ADP[c] + H[c] + MG[c] + PI[c] thymidine phosphorylase [c]: DT + PI ⇔ DR1P + THY 5'-nucleotidase (a-glutamyl-2'-deoxythymidine monophosphate) [c]: gludTMP + H2O ⇒ gludT + PI oligopeptide (Pro) transport via ABC system ATP[c] + H2O[c] + ProPro[e] ⇒ ADP[c] + H[c] + PI[c] + ProPro[c] 5'-nucleotidase (1-ethyl-2'-deoxyguanosine monophosphate) [c]: e1dGMP + H2O ⇒ e1dG + PI 5'-nucleotidase (3-methyl-2'-deoxyguanosine monophosphate) [c]: H2O + m3dGMP ⇒ m3dG + PI 5'-nucleotidase (2-hydroxy-2'-deoxyadenosine monophosphate) [c]: H2O + oxo2dAMP ⇒ oxo2dA + PI copper-transporting ATPase ATP[c] + CU[e] + H2O[c] ⇒ ADP[c] + CU[c] + H[c] + PI[c] 5'-nucleotidase (PSIURIMP) [c]: H2O + PSIURIMP ⇒ PI + PSIURI Negative supercoiling (topoisomerase I) [c]: (2) ATP + (2) H2O ⇒ (2) ADP + (2) H + (2) PI 5'-nucleotidase (UmMP) [c]: H2O + UmMP ⇒ PI + Um nicotinic acid mononucleotide pyrophosphorylase [c]: ATP + (3) H + H2O + NAC + PRPP ⇒ ADP + NAMN + PI + PPI Protein degradation (ASP) [c]: AspAsp + ATP + (2) H2O ⇒ ADP + (2) ASP + H + PI Protein degradation (ARG) [c]: ArgArg + ATP + (2) H2O ⇒ ADP + (2) ARG + H + PI L-glutamine transport via ABC system ATP[c] + GLN[e] + H2O[c] ⇒ ADP[c] + GLN[c] + H[c] + PI[c] oligopeptide (His) transport via ABC system ATP[c] + H2O[c] + HisHis[e] ⇒ ADP[c] + H[c] + HisHis[c] + PI[c] oxaloacetate carboxylase [c]: ATP + CO2 + H2O + PYR ⇔ ADP + (2) H + OA + PI 5'-nucleotidase (N4-(2-Deoxy-alpha,beta-D-erythro-pentofuranosyl)-4,6-diamino-5-formamidopyrimidine monophosphate) [c]: FAPydAMP + H2O ⇒ FAPydA + PI oligopeptide (Val) transport via ABC system ATP[c] + H2O[c] + ValVal[e] ⇒ ADP[c] + H[c] + PI[c] + ValVal[c] 5'-nucleotidase (2'-deoxycytidine monophosphate-[6,4]-2'-deoxycytidine monophosphate) [c]: dCMP64dCMP + (2) H2O ⇒ dC64dC + (2) PI oligopeptide (Gly) transport via ABC system ATP[c] + GlyGly[e] + H2O[c] ⇒ ADP[c] + GlyGly[c] + H[c] + PI[c] putrescine transport via ABC system ATP[c] + H2O[c] + PTRC[e] ⇒ ADP[c] + H[c] + PI[c] + PTRC[c] 5'-nucleotidase (s4UMP) [c]: H2O + s4UMP ⇒ PI + s4U RNA cleavage (UMP) [c]: GTP + (2) H2O + UpUp ⇒ GDP + (2) H + PI + (2) UMP sugar phosphatase (fructose-6-phosphate) [c]: F6P + H2O ⇒ FRU + PI FtsZ ring contraction [c]: (18) H2O + (2) MG_224_9MER_GTP ⇒ (18) H + (2) MG_224_9MER_GDP + (18) PI DNA recombination strand exchange [c]: ATP + H2O ⇒ ADP + H + PI nickel transport via ABC system ATP[c] + H2O[c] + NI[e] ⇒ ADP[c] + H[c] + NI[c] + PI[c] Protein degradation (HIS) [c]: ATP + (2) H2O + HisHis ⇒ ADP + H + (2) HIS + PI oligopeptide (Lys) transport via ABC system ATP[c] + H2O[c] + LysLys[e] ⇒ ADP[c] + H[c] + LysLys[c] + PI[c] 2-aminoethylphosphonate transport via ABC system AEPP[e] + ATP[c] + H2O[c] ⇒ ADP[c] + AEPP[c] + H[c] + PI[c] Protein degradation (MET) [c]: ATP + (2) H2O + MetMet ⇒ ADP + H + (2) MET + PI oligopeptide (Leu) transport via ABC system ATP[c] + H2O[c] + LeuLeu[e] ⇒ ADP[c] + H[c] + LeuLeu[c] + PI[c] nicotinate-nucleotide adenylyltransferase [c]: ATP + NH3 + NR ⇒ ADP + NMN + PI purine-nucleoside phosphorylase (Adenosine) [c]: AD + R1P ⇔ ADN + (2) H + PI 5'-nucleotidase (alpha-putrescinyl-2'-deoxythymidine monophosphate) [c]: H2O + putdTMP ⇒ PI + putdT 5'-nucleotidase (5-Carbouy-2'-deoxyuridine monophosphate) [c]: c5dUMP + H2O ⇒ c5dU + PI Manganese-transporting ATPase ATP[c] + H2O[c] + MN[e] ⇒ ADP[c] + H[c] + MN[c] + PI[c] iron (III) transporting ATPase ATP[c] + FE3[e] + H2O[c] ⇒ ADP[c] + FE3[c] + H[c] + PI[c] deoxyuridine phosphorylase [c]: DU + PI ⇔ DR1P + URA 5'-nucleotidase (5-hydroxy-6-hydroxy-2'-deoxythymidine monophosphate) [c]: H2O + ho5ho6dTMP ⇒ ho5ho6dT + PI 5'-nucleotidase (6-ethyl-2'-deoxyadenosine monophosphate) [c]: e6dAMP + H2O ⇒ e6dA + PI calcium-transporting ATPase ATP[c] + CA[e] + H2O[c] ⇒ ADP[c] + CA[c] + H[c] + PI[c] 5'-nucleotidase (7-methyl-2'-deoxyguanosine monophosphate) [c]: H2O + m7dGMP ⇒ m7dG + PI Ribosome assembly (RbgA) [c]: GTP + H2O ⇒ GDP + H + PI inorganic diphosphatase [c]: H2O + PPI ⇒ H + (2) PI 5'-nucleotidase (k2CMP) [c]: H2O + k2CMP ⇒ k2C + PI 5'-nucleotidase (5-Hydroxy-2'-deoxycytidine monophosphate) [c]: H2O + ho5dCMP ⇒ ho5dC + PI Protein degradation (TRP) [c]: ATP + (2) H2O + TrpTrp ⇒ ADP + H + PI + (2) TRP

Metadata
Created	2012-10-01 15:07:06
Last updated	2012-10-01 15:12:28