O6mGN – 6'-O-methylguanine

Name
WID	O6mGN
Name	6'-O-methylguanine
Traditional name	6-methoxy-9H-purin-2-amine
IUPAC name	6-methoxy-9H-purin-2-amine
Cross references	ChEBI: 479073, PubChem: 85668184

Classification
Type	modified_nucleobase_methylation

Structure
Empirical formula (pH 7.5)	H₇C₆N₅O₁
SMILES (pH 7.5)	COC1=NC(N)=NC2=C1N=CN2
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	165.15
van der Waals volume (pH 7.5; Å³ molecule^‑1)	133.19
pI	7.13
logP	-0.01000
logD (pH 7.5)	-0.0500

Function
Reaction participant	DNA base methylation (guanine ==> 6'-O-methylguanine; N-methyl-N'-nitro-N-nitrosoguanidine) [c]: GN + MNNG ⇒ NNG + O6mGN DNA base methylation (guanine ==> 6'-O-methylguanine; dimethyl sulfate) [c]: GN + MMSO4 ⇒ MSO4 + O6mGN DNA base methylation (guanine ==> 6'-O-methylguanine; N-methyl-N-nitrosourea) [c]: GN + MNU ⇒ NU + O6mGN DNA base methylation (guanine ==> 6'-O-methylguanine; methyl methanesulphonate) [c]: GN + MMS ⇒ MS + O6mGN

Metadata
Created	2012-10-01 15:07:05
Last updated	2012-10-01 15:12:26