O2mTHY – 2'-O-methylthymine

Name
WID	O2mTHY
Name	2'-O-methylthymine
Traditional name	2-methoxy-5-methyl-1H-pyrimidin-4-one
IUPAC name	2-methoxy-5-methyl-1,4-dihydropyrimidin-4-one
Cross references	PubChem: 24518692, CAS: 25902-91-4

Classification
Type	modified_nucleobase_methylation

Structure
Empirical formula (pH 7.5)	H₈C₆N₂O₂
SMILES (pH 7.5)	CC1=CNC(=NC1=O)OC
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	140.14
van der Waals volume (pH 7.5; Å³ molecule^‑1)	124.06
pI	10.02
logP	0.130
logD (pH 7.5)	0.0700

Function
Reaction participant	DNA base methylation (thymine ==> 2'-O-methylthymine; N-methyl-N-nitrosourea) [c]: MNU + THY ⇒ NU + O2mTHY DNA base methylation (thymine ==> 2'-O-methylthymine; N-methyl-N'-nitro-N-nitrosoguanidine) [c]: MNNG + THY ⇒ NNG + O2mTHY

Metadata
Created	2012-10-01 15:07:04
Last updated	2012-10-01 15:12:25