NrdEF_maintenance – ribonucleoside-diphosphate reductase maintenance

Name
WID NrdEF_maintenance View in model
Name ribonucleoside-diphosphate reductase maintenance View in model
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: (2) FMNH2 + (2) MG_124_MONOMER + MG_229_231_TETRAMER_ox ⇒ (2) FMN + (2) H2O + (2) MG_124_MONOMER_ox + MG_229_231_TETRAMER View in model
 
Catalysis
Enzyme MG_230_MONOMER [c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
 
Associations
Process Process_Metabolism View in model
 
Comments
Comments NrdI (MG_230) removes NrdF oxygens Trx (MG_124) reduces NrdE disulfide bonds References Cotruvo and Stubbe, 2008 [PUB_0160]
References

  1. Cotruvo JA Jr, Stubbe J. NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase. Proc Natl Acad Sci U S A 105, 14383-8 (2008). WholeCell: PUB_0160, PubMed: 18799738
 
Metadata
Created 2012-10-01 15:08:53
Last updated 2012-10-01 15:17:27