Note_ProteinActivation – ProteinActivation

WID Note_ProteinActivation
Name ProteinActivation
Comments Chemical regulation of protein activity was reconstructed from the primary literature. In addition to the transcriptional regulators, HPr(Ser) kinase/phosphatase (MG_085_HEXAMER) is regulated by glucose-6-phosphate (G6P) levels [PUB_0454, PUB_0458]. See Note_TranscriptionalRegulation for more information about the reconstruction of the chemical regulation of transcriptional regulators.
  1. Deutscher J, Saier MH Jr. ATP-dependent protein kinase-catalyzed phosphorylation of a seryl residue in HPr, a phosphate carrier protein of the phosphotransferase system in Streptococcus pyogenes. Proc Natl Acad Sci U S A 80, 6790-4 (1983). WholeCell: PUB_0458, PubMed: 6359157

  2. Nessler S, Fieulaine S, Poncet S, Galinier A, Deutscher J, Janin J. HPr kinase/phosphorylase, the sensor enzyme of catabolite repression in Gram-positive bacteria: structural aspects of the enzyme and the complex with its protein substrate. J Bacteriol 185, 4003-10 (2003). WholeCell: PUB_0454, PubMed: 12837773

Created 2012-10-01 15:07:34
Last updated 2012-10-01 15:13:58