Note_GeneEssentiality – GeneEssentiality

WID Note_GeneEssentiality
Name GeneEssentiality
Comments M. genitalium gene essentiality was determined by random transposon mutagenesis by Glas et al [PUB_0193] and Hutchison et al [PUB_0595]. The essentiality B. subtilis [PUB_0598], E. coli [PUB_0599], H. influenze [PUB_0600], and other bacteria have also been determined. Computational scientists have used these studies as the basis for prediction of the minimal gene complement necessary for life [PUB_0596, PUB_0597].
  1. Akerley BJ, Rubin EJ, Novick VL, Amaya K, Judson N, Mekalanos JJ. A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc Natl Acad Sci U S A 99, 966-71 (2002). WholeCell: PUB_0600, PubMed: 11805338

  2. Gerdes SY, Scholle MD, Campbell JW, Balázsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabási AL, Oltvai ZN, Osterman AL. Experimental determination and system level analysis of essential genes in Escherichia coli MG1655. J Bacteriol 185, 5673-84 (2003). WholeCell: PUB_0599, PubMed: 13129938

  3. Gil R, Silva FJ, Peretó J, Moya A. Determination of the core of a minimal bacterial gene set. Microbiol Mol Biol Rev 68, 518-37 (2004). WholeCell: PUB_0597, PubMed: 15353568

  4. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  5. Hutchison CA, Peterson SN, Gill SR, Cline RT, White O, Fraser CM, Smith HO, Venter JC. Global transposon mutagenesis and a minimal Mycoplasma genome. Science 286, 2165-9 (1999). WholeCell: PUB_0595, PubMed: 10591650

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  7. Kobayashi K, Ehrlich SD, Albertini A, Amati G, Andersen KK, Arnaud M, Asai K, Ashikaga S, Aymerich S, Bessieres P, Boland F, Brignell SC, Bron S, Bunai K, Chapuis J, Christiansen LC, Danchin A, Débarbouille M, Dervyn E, Deuerling E, Devine K, Devine SK, et al. Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A 100, 4678-83 (2003). WholeCell: PUB_0598, PubMed: 12682299

  8. Mushegian AR, Koonin EV. A minimal gene set for cellular life derived by comparison of complete bacterial genomes. Proc Natl Acad Sci U S A 93, 10268-73 (1996). WholeCell: PUB_0596, PubMed: 8816789

Created 2012-10-01 15:07:34
Last updated 2012-10-01 15:13:57