NADR1 – nicotinamide-nucleotide adenylyltransferase
Name | ||
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WID | NADR1 |
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Name | nicotinamide-nucleotide adenylyltransferase |
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Cross references | EC: 2.7.7.1, BioCyc: 2.7.7.1-RXN, SABIO-RK: 8751, BiGG: NMNAT, KEGG: R00137 | |
Classification | ||
Type | chemical |
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Reaction | ||
Stoichiometry | [c]: ATP + H + NMN ⇒ NAD + PPI |
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Catalysis | ||
Enzyme | MG_240_HEXAMER [c] |
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Optimal pH | 8.6 (dimensionless) |
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Optimal temperature | 80.0 (C) |
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Energetics | ||
Is spontaneous (pH 7.5, 25C, I = 0) | False |
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ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) | 0.400 | |
Keq | 0.514590152372 () |
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Kinetics | ||
Forward kinetics | v = Vmax * [ATP] * [NMN] / (Km1 * Km2 + Km1 * [NMN] + Km2 * [ATP]); Km1 = 160 (nM), Km2 = 80 (nM), Vmax = 600.0 1/min (Show evidence) |
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Associations | ||
Pathways | COFACTOR_PROSTHETIC_BIOSYNTHESIS | |
Process | Process_Metabolism |
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Comments | ||
References |
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Metadata | ||
Created | 2012-10-01 15:08:52 | |
Last updated | 2012-10-01 15:17:25 |