MutM_oxo8GN – base excision (8-Oxo-guanine; 8-hydroxyguanine)

Name
WID MutM_oxo8GN View in model
Name base excision (8-Oxo-guanine; 8-hydroxyguanine) View in model
Cross references EC: 3.2.2, BiGG: oxo8dGMP, BioCyc: oxo8GN
 
Classification
Type base_excision_repair_base_excision View in model
 
Reaction
Stoichiometry [c]: H2O + oxo8dGMP ⇒ DR5P + oxo8GN View in model
 
Catalysis
Enzyme MG_498_MONOMER [c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
 
Kinetics
Forward kinetics Km = 1863000 (nM), Vmax = 0.0834 1/min View in model
 
Associations
Process Process_DNARepair View in model
 
Comments
Comments Reaction Vmax and Km cataloged in [PUB_0488].
References

  1. Sokhansanj BA, Rodrigue GR, Fitch JP, Wilson DM 3rd. A quantitative model of human DNA base excision repair. I. Mechanistic insights. Nucleic Acids Res 30, 1817-25 (2002). WholeCell: PUB_0488, PubMed: 11937636
 
Metadata
Created 2012-10-01 15:08:52
Last updated 2012-10-01 15:17:24