MSO4 – Methyl sulfate

Name
WID	MSO4
Name	Methyl sulfate
Traditional name	methyl sulfate
IUPAC name	methoxysulfonic acid
Cross references	ChEBI: 17760, PubChem: 5667, KEGG: C02704

Classification
Type	alkylating_byproduct_methylation

Structure
Empirical formula (pH 7.5)	H₄C₁O₄S₁
SMILES (pH 7.5)	COS(=O)(=O)O
Charge (pH 7.5)	-1
Is hydrophobic	False
Molecular weight (Da)	112.10
van der Waals volume (pH 7.5; Å³ molecule^‑1)	81.86
Δ_fG^'o (pH 7.5, 25C, I = 0; kJ mol^‑1)	-748.20
logP	-0.460
logD (pH 7.5)	-2.84

Function
Reaction participant	DNA base methylation (cytosine ==> 3-methylcytosine; dimethyl sulfate) [c]: CSN + MMSO4 ⇒ m3CSN + MSO4 DNA base methylation (adenine ==> 1-methyladenine; dimethyl sulfate) [c]: AD + H + MMSO4 ⇒ m1AD + MSO4 DNA base methylation (adenine ==> 3-methyladenine; dimethyl sulfate) [c]: AD + MMSO4 ⇒ m3AD + MSO4 DNA base methylation (guanine ==> 7-methylguanine; dimethyl sulfate) [c]: GN + H + MMSO4 ⇒ m7GN + MSO4 DNA base methylation (adenine ==> 7-methyladenine; dimethyl sulfate) [c]: AD + MMSO4 ⇒ m7AD + MSO4 ... 2 more DNA base methylation (guanine ==> 6'-O-methylguanine; dimethyl sulfate) [c]: GN + MMSO4 ⇒ MSO4 + O6mGN DNA base methylation (guanine ==> 3-methylguanine; dimethyl sulfate) [c]: GN + MMSO4 ⇒ m3GN + MSO4

Comments
Comments	byproduct of DNA methylation by MMSO4

Metadata
Created	2012-10-01 15:07:03
Last updated	2012-10-01 15:12:23