MG_498_MONOMER – formamidopyrimidine-DNA glycosylase
Name | ||
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WID | MG_498_MONOMER |
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Name | formamidopyrimidine-DNA glycosylase |
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Cross references | PDB: 1K82 | |
Genetics | ||
Gene | MG_498 |
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Structure | ||
Sequence | 1 51 101 151 201 251 MPELPEVTTVINELKETVLNKPLDQVQVNLRKVLKNIDPQLLNKQLKNQF FTDIKRKGKYIIFLLSNGLYLVSHLRMEGKYFFEERGSKFNQKHVLVEFH FDDGSQLNYHDTRQFGTFHLYEKLEQAAQLNKLAFDPLEAGFDYRKIFQK AQNSKRKVKTFILDQTVISGIGNIYADEILFASKINPETMVDQLTIKEIE ILCKNATKILAKAIVMKGTTISSFSFKKDHTGGYQNFLKVHTKKDQPCSV CNQLIVKKKINGRGSYFCLNCQKITTKVSTKLNP* 50 100 150 200 250 285 |
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Is N‑terminal methionine cleaved | Yes |
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Prosthetic groups |
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DNA footprint | Length: 9 (nt), Binding: dsDNA, Region: dsDNA |
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Empirical formula (pH 7.5) | H2387C1487N395O418S9 | |
Molecular weight (pH 7.5; Da) | 32774.75 |
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Extinction coefficient (260 nm, 25C, pH 7.0) |
14035 | |
Instability index | 21.84 | |
Is stable | True | |
Aliphatic index | 90.60 | |
GRAVY (25C, pH 7.0) | -0.380 | |
Half life (OD (600 nm) = 0.3, M9 media, 36C; min) |
1200 |
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Synthesis | ||
Localization | c |
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Function | ||
Enzyme |
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Reaction participant |
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Comments | ||
Comments | Functional Macromolecule Functional as monomer [PUB_0074]. Coenzymes Interacts with 1 ZN per monomer as prosthetic group [74]. N-terminal methionine cleavage Shewanella oneidensis MR-1 homolog undergoes N-terminal methionine cleavage [PUB_0280]. DNA-binding Fpg footprint is 9 nt [PUB_0719]. Ogg1 footprint is 10 nt [PUB_0719, PUB_0720, PUB_0721, PUB_0722]. Fpg footprint is 12 nt [PUB_0717]. | |
References |
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Metadata | ||
Created | 2012-10-01 15:07:55 | |
Last updated | 2012-10-01 15:14:38 |