MG_467 – salivaricin A ABC transporter, ATP-binding protein

Name
WID MG_467 View in model
Name salivaricin A ABC transporter, ATP-binding protein View in model
Protein product MG_467_MONOMER
Cross references GenBank: AAC72487.1, CMR: MG_467, BioCyc: MG_467, SwissProt: P47705
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 567555573491 MG_463 MG_464 MG_465 MG_467 MG_468 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 570055 (nt), Length: 936 (nt), Direction: Reverse, G/C content: 30.8%, Sequence:
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ATGAAAAAAGGCAATAAAACTGTTTGAAATGAATGTATTGATATCTTAGA
TAACGTTAAAAGTCCTTCTTTTAGTGCCAATTTCGATGATTATTTCAAAA
AGAGTAAATCTAAACCTCCTAAGAAGAATAAAAAAGTTTTAAATAACATT
AAAAAAGCTGAGCTAAAGCTCAAAAAGAAAGCTAATAAAAAGCAAAAAGC
CAATACCTTATATATCCCTCCTTTTGCTCAACAAGCTAAGGGAATTGTTA
TTACCATCAATAAGATGTGAAAAAATGTTCATAATGATGATTCAAAGCAA
GAGATTTCTATCCTTTCAGATGTTTCTTTACAGATAGCTTATGGTGAAAT
AGTAATCATTTTAGGTTCTTCAGGATCAGGTAAAACAACCCTTTTAAACC
TGATAGGTGGTTATGATTCTATCTCGTTAGGGAGTTGTATCGTAGCAAAC
TGTCCATTAGAAAAATGTACTAGTGAACAACTTTTAACTTATCGAAAGAA
TAACCTTGGTTATGTCTATCAGCGTTATAATCTGATTGAATTGTTAAGTG
CTTATGATAATATTGCCATTTCACAAAACTTAATTCCCAAATATCAAAGA
CGACTTGATATAGAAGAGTTGGCTGAAAAATTAGATATTAAAGAAATCTT
GTATAAATTTCCTTATGAGATGTCAGGTGGGCAAAAACAAAGAGTGGCCA
TCGCCCGTGCTATTATTAAAGAACCTAAACTATTACTTTGTGATGAACCT
ACTGGTGCACTTGATAGTAATTCTGCGGAAAATATCATTAATTTATTACA
AACAATTAACAAAACATATAAGCAAACCATCCTAATGGTTACCCATGATG
TAAGCCTAACAAGGATAGCTAATAGAATCATTAAAATTTCAGATGGTAAA
ATAGTATCTAACCAATTAGTCAGACCCTTAGTTTAG
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936
 View in model
Transcription unit TU_333 View in model
Empirical formula (pH 7.5) H10008C9071N3813O6483P936
Molecular weight (pH 7.5; Da) 305159.26 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
 View in model
Relative expression
0.851454 (dimensionless) (Show evidence)
 View in model
Half life
4.425 (min) (Show evidence)
 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)		 9758600
pI 3.84
 
Comments
Comments no predicted substrate binding protein in M. genitalium; macrolide-specific ABC transporter [PUB_0110, PUB_0440]; salivaricin A is a lantibiotic; no lantibiotic genes in M. genitalium;
References

  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 31, 474-7 (2003). WholeCell: PUB_0110, PubMed: 12520055, URL: http://www.ncbi.nlm.nih.gov/Structure/

  3. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  4. Ren Q, Chen K, Paulsen IT. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Nucleic Acids Res 35, D274-9 (2007). WholeCell: PUB_0440, PubMed: 17135193, URL: http://membranetransport.org/

  5. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319
 
Metadata
Created 2012-10-01 15:07:30
Last updated 2012-10-01 15:13:47