MG_409_DIMER – phosphate transport system regulatory protein PhoU, putative

WID MG_409_DIMER View in model
Name phosphate transport system regulatory protein PhoU, putative View in model
Biosynthesis [c]: (2) MG_409_MONOMERMG_409_DIMER View in model
No. subunits 2
Empirical formula (pH 7.5) H3886C2462N638O706S12
Molecular weight (pH 7.5; Da) 54103.67 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)
1200.00 View in model
Formation process Process_MacromolecularComplexation View in model
Localization c
Regulatory rule PI > 20 View in model
Complex subunit phosphate transport system regulatory protein PhoU, putative
[c]: (2) MG_409_MONOMERMG_409_DIMER
View in model
Comments Composition [PUB_0339]. Regulation: PhoU (MG_409) regulates phosphate transport through two mechanisms at high phosphate levels (>20 mM): 1) inactivates PstABCS (MG_410, MG_411, MG_412), and 2) through PhoR transcriptional repression of the PhoU, PstABCS operon [PUB_0218, PUB_0453].
  1. Muda M, Rao NN, Torriani A. Role of PhoU in phosphate transport and alkaline phosphatase regulation. J Bacteriol 174, 8057-64 (1992). WholeCell: PUB_0453, PubMed: 1459954

  2. Oganesyan V, Oganesyan N, Adams PD, Jancarik J, Yokota HA, Kim R, Kim SH. Crystal structure of the PhoU-like phosphate uptake regulator from Aquifex aeolicus.. J Bacteriol 187, 4238-44 (2005). WholeCell: PUB_0339, PubMed: 15937186

  3. Rice CD, Pollard JE, Lewis ZT, McCleary WR. Employment of a promoter-swapping technique shows that PhoU modulates the activity of the PstSCAB2 ABC transporter in Escherichia coli. Appl Environ Microbiol 75, 573-82 (2009). WholeCell: PUB_0218, PubMed: 19047379

Created 2012-10-01 15:07:41
Last updated 2012-10-01 15:14:15