MG_367_DIMER – ribonuclease III

WID MG_367_DIMER View in model
Name ribonuclease III View in model
Biosynthesis [c]: (2) MG_367_MONOMERMG_367_DIMER View in model
No. subunits 2
Empirical formula (pH 7.5) H4340C2774N694O802S14
Molecular weight (pH 7.5; Da) 60693.05 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)
1200.00 View in model
Formation process Process_MacromolecularComplexation View in model
Localization c
Enzyme View in model
Complex subunit ribonuclease III
[c]: (2) MG_367_MONOMERMG_367_DIMER
View in model
Parameters Parameter_0132: enzymeSpecificRate_RNAseIII = 7.7 1/s View in model
Comments Ribonuclease III is a double strand-specific endoribonuclease. RNAse III mature rRNA and scRNA and initiates decay of some mRNAs by cleaving their 5' UTR. RNAse III functions as a homodimer with a Mg2+ cofactor. References: [PUB_0038, PUB_0039, PUB_0649].
  1. Deutscher MP. Maturation and degradation of ribosomal RNA in bacteria. Prog Mol Biol Transl Sci 85, 369-91 (2009). WholeCell: PUB_0038, PubMed: 19215777

  2. Nakanishi K, Nureki O. Recent progress of structural biology of tRNA processing and modification. Mol Cells 19, 157-66 (2005). WholeCell: PUB_0649, PubMed: 15879697

  3. Nicholson AW. Function, mechanism and regulation of bacterial ribonucleases. FEMS Microbiol Rev 23, 371-90 (1999). WholeCell: PUB_0039, PubMed: 10371039

Created 2012-10-01 15:07:41
Last updated 2012-10-01 15:14:14