MG_298_MONOMER – chromosome segregation protein SMC

Name
WID MG_298_MONOMER View in model
Name chromosome segregation protein SMC View in model
 
Genetics
Gene MG_298 View in model
 
Structure
Sequence
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101
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651
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951
MVFLKRFRAYGFKSYADEITIDFTHSMTGIVGPNGSGKSNVVDALKWVLG
ERSMKHLRSKSGDDMIFFGSKDKPASKLAEIELTFDNSNRLLHDSRKEIS
VMRRVYRGSGQSEYFINSNPATLKEISGIFADIGLEKGSLGIISQGSVSW
FVEAKPEERRKIFEDASGIGRYTKRKEEVVNQLNRTLINLKQVSVVLNEL
KKDLKKLTLQAEKAQQFIRVKNELKELELAVLVGEYLQAQTELDKFNFQI
NSSEHDFKIHEPQLELLEEQIVIFNSRFHSADMQSNELQKELQDIYQKIN
ELEQRKVIIDVQLRQGFSQKDEKQKAAALKKLILVDQTQLDGFENQLSNS
KTTITDLEKLINEQKSLVDQIKLQIEKNTADLIYQRSLKTIIELQTNELK
KTNNANILVKNANALTGILNTLGTFLKFDKQYEKAILKALGKSIGYLVVN
NNNAAIQAIDFLVKNEIGKVTFLPLDDVASDTKITNEHMEILKQLDGFLG
VCSDHVKCDPLFQPVVNTLLAQVIIAKDLNSAINLSNYTYKLYRIVTLDG
ETVYAGGIINGGFEKTNLSDGYLSSASLDNEQNINKLENNERELKKELTE
LEVKLDEMNRKLKYEELLQAKFIERIVQIKKIILELKMEYEQLTNTTFDG
KKAVASEAELIHSLNSAWAKRDEINSKLKLNQELKLQLAKTIKQSEEKIV
DLRALLDEQRAKLVSAREGKIRFENTIQNITEKINSVYKMTMEFAIANHN
KPVKLSSMQAHNKIAKLQNQLNEMGVINMESIAEISEKQKRFDDINAEYE
SAQQAVENLQKAITEIDEIASNEFDQLIQKLNQELPKTFKYLFGGGSCQI
RYTDPSNVLVSGIDVFANPPGKNIANLMLLSGGEKTLVALSVLFSILKVS
AFPLVILDEAESALDPANVERFANIIKTASKNTQFLIITHRQGTMMKCDM
LLGAAMQTKGVTKTFAVELENAEKYVSENDSN*
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850
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950
983
 View in model
Is N‑terminal methionine cleaved
No
 View in model
Empirical formula (pH 7.5) H8010C4939N1332O1518S23
Molecular weight (pH 7.5; Da) 111075.63 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)		 49780
Instability index 29.74
Is stable True
Aliphatic index 99.81
GRAVY (25C, pH 7.0) -0.357
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)		 1200 View in model
 
Synthesis
Localization c View in model
 
Function
Complex subunit chromosome segregation protein SMC
[c]: (2) MG_213_MONOMER + (2) MG_214_MONOMER + (2) MG_298_MONOMER ⇒ MG_213_214_298_6MER		 View in model
 
Comments
Comments Functional Macromolecule Functional as homodimer [PUB_0336, PUB_0337].
References

  1. Mascarenhas J, Volkov AV, Rinn C, Schiener J, Guckenberger R, Graumann PL. Dynamic assembly, localization and proteolysis of the Bacillus subtilis SMC complex. BMC Cell Biol 6, 28 (2005). WholeCell: PUB_0337, PubMed: 15987505

  2. Tadesse S, Mascarenhas J, Kösters B, Hasilik A, Graumann PL. Genetic interaction of the SMC complex with topoisomerase IV in Bacillus subtilis. Microbiology 151, 3729-37 (2005). WholeCell: PUB_0336, PubMed: 16272394
 
Metadata
Created 2012-10-01 15:07:57
Last updated 2012-10-01 15:14:40