MG_287_MONOMER_ACP – holo acyl carrier protein

Name
WID	MG_287_MONOMER_ACP
Name	holo acyl carrier protein

Structure
Biosynthesis	[c]: COA + MG_287_MONOMER ⇒ H + PAP + MG_287_MONOMER_ACP
No. subunits	1
Empirical formula (pH 7.5)	H₇₃₆C₄₄₅N₁₁₂O₁₃₆P₁S₄
Molecular weight (pH 7.5; Da)	9990.48
Extinction coefficient (260 nm, 25C, pH 7.0)	0.0
Half life (OD (600 nm) = 0.3, M9 media, 36C; min)	1159.24

Synthesis
Formation process	Process_Metabolism
Localization	c

Function
Reaction participant	glycerol-3-phosphate acyltransferase (C16:1) [c]: GL3P + H + MG_287_MONOMER_hdeACP ⇒ HDECEG3P + MG_287_MONOMER_ACP glycerol-3-phosphate acyltransferase (C14:0) [c]: GL3P + MG_287_MONOMER_myrsACP ⇒ H + MG_287_MONOMER_ACP + TDECG3P acyl-[acyl-carrier-protein] synthetase (n-C16:1) [c]: ATP + HDCEA + MG_287_MONOMER_ACP ⇒ AMP + MG_287_MONOMER_hdeACP + PPI glycerol-3-phosphate acyltransferase (C18:0) [c]: GL3P + MG_287_MONOMER_ocdcaACP ⇒ H + MG_287_MONOMER_ACP + ODECG3P 1-tetradecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C12:0) DDECG3P[c] + MG_287_MONOMER_ddcaACP[c] ⇒ MG_287_MONOMER_ACP[c] + PA120[m] ... 17 more 1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:0) (2) H[c] + HDECG3P[c] + MG_287_MONOMER_palmACP[c] ⇒ MG_287_MONOMER_ACP[c] + PA160[m] glycerol-3-phosphate acyltransferase (C14:1) [c]: GL3P + MG_287_MONOMER_tdeACP ⇒ H + MG_287_MONOMER_ACP + TDECEG3P acyl-[acyl-carrier-protein] synthetase (n-C12:0) [c]: ATP + DDCA + MG_287_MONOMER_ACP ⇒ AMP + MG_287_MONOMER_ddcaACP + PPI 1-octadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C18:1) MG_287_MONOMER_octeACP[c] + ODEC11GP[c] ⇒ MG_287_MONOMER_ACP[c] + PA181[m] acyl-[acyl-carrier-protein] synthetase (n-C18:0) [c]: ATP + MG_287_MONOMER_ACP + OCDCA ⇒ AMP + MG_287_MONOMER_ocdcaACP + PPI acyl-[acyl-carrier-protein] synthetase (n-C16:0) [c]: ATP + HDCA + MG_287_MONOMER_ACP ⇒ AMP + MG_287_MONOMER_palmACP + PPI 1-octadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C18:0) MG_287_MONOMER_ocdcaACP[c] + ODECG3P[c] ⇒ MG_287_MONOMER_ACP[c] + PA180[m] glycerol-3-phosphate acyltransferase (C16:0) [c]: GL3P + MG_287_MONOMER_palmACP ⇒ (3) H + HDECG3P + MG_287_MONOMER_ACP glycerol-3-phosphate acyltransferase (C12:0) [c]: GL3P + MG_287_MONOMER_ddcaACP ⇒ DDECG3P + H + MG_287_MONOMER_ACP acyl-carrier protein synthase [c]: COA + MG_287_MONOMER ⇒ H + MG_287_MONOMER_ACP + PAP acyl-[acyl-carrier-protein] synthetase (n-C14:0) [c]: ATP + MG_287_MONOMER_ACP + TTDCA ⇒ AMP + MG_287_MONOMER_myrsACP + PPI 1-tetradecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C14:0) MG_287_MONOMER_myrsACP[c] + TDECG3P[c] ⇒ MG_287_MONOMER_ACP[c] + PA140[m] acyl-[acyl-carrier-protein] synthetase (n-C14:1) [c]: ATP + MG_287_MONOMER_ACP + TTDCEA ⇒ AMP + MG_287_MONOMER_tdeACP + PPI acyl-[acyl-carrier-protein] synthetase (n-C18:1) [c]: ATP + MG_287_MONOMER_ACP + OCDCEA ⇒ AMP + MG_287_MONOMER_octeACP + PPI 1-tetradec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C14:1) MG_287_MONOMER_tdeACP[c] + TDECEG3P[c] ⇒ MG_287_MONOMER_ACP[c] + PA141[m] glycerol-3-phosphate acyltransferase (C18:1) [c]: GL3P + MG_287_MONOMER_octeACP ⇒ H + MG_287_MONOMER_ACP + ODEC11GP 1-hexadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:1) HDECEG3P[c] + MG_287_MONOMER_hdeACP[c] ⇒ (2) H[c] + MG_287_MONOMER_ACP[c] + PA161[m]
Complex subunit	holo acyl carrier protein [c]: COA + MG_287_MONOMER ⇒ H + PAP + MG_287_MONOMER_ACP

Comments
Comments	Acyl carrier protein (ACP) carries fatty acid chains via a thioester linkage to a phosphopantetheine prosthetic group as the chains are elongated [PUB_0006]. AcpS transfers CoA to apo-ACP, forming holo-ACP [PUB_0006]. Aas transfers fatty acyl chains to ACP [PUB_0006].
References	Keseler IM, Bonavides-Martínez C, Collado-Vides J, Gama-Castro S, Gunsalus RP, Johnson DA, Krummenacker M, Nolan LM, Paley S, Paulsen IT, Peralta-Gil M, Santos-Zavaleta A, Shearer AG, Karp PD. EcoCyc: a comprehensive view of Escherichia coli biology. Nucleic Acids Res 37, D464-70 (2009). WholeCell: PUB_0006, PubMed: 18974181

Metadata
Created	2012-10-01 15:07:40
Last updated	2012-10-01 15:14:11