MG_127_MONOMER – Spx subfamily protein
Name | ||
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WID | MG_127_MONOMER |
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Name | Spx subfamily protein |
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Genetics | ||
Gene | MG_127 |
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Structure | ||
Sequence | 1 51 101 MKKAGKKNSDAGKTFILISSSCSSCQKAIEFFDQNKISYVVENFYKKPIS DKRFKDILSLSEDGTESLFSKRADQIKATNSVSVEELSISELIKLVRERP SLLRRPIIIQYNSSGIPKRMRIGYNSSEIKVFERKLIEPKPIIQQ* 50 100 146 |
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Is N‑terminal methionine cleaved | No |
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Disulfide_bonds | MG_127_MONOMER_ox: 22-25 |
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DNA footprint | Length: 25 (nt), Binding: dsDNA, Region: dsDNA |
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Empirical formula (pH 7.5) | H1222C739N202O220S4 | |
Molecular weight (pH 7.5; Da) | 16585.04 |
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Extinction coefficient (260 nm, 25C, pH 7.0) |
6210 | |
Instability index | 51.12 | |
Is stable | False | |
Aliphatic index | 90.14 | |
GRAVY (25C, pH 7.0) | -0.454 | |
Half life (OD (600 nm) = 0.3, M9 media, 36C; min) |
1200 |
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Synthesis | ||
Localization | c |
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Regulation | ||
Regulatory rule | stimulus_thiolStress |
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Function | ||
Transcriptional regulation |
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Reaction participant |
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Complex subunit | oxidized Spx subfamily protein [c]: MG_127_MONOMER ⇒ (2) H + MG_127_MONOMER_ox |
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Comments | ||
Comments | Functional Macromolecule Functional as monomer [PUB_0112]. Transcriptional Regulation Affects transcription by interacting solely with RNA polymerase, and does not directly bind DNA [PUB_0434]. Together with RNAP spx has 43-50 nt footprint [PUB_0728]. RNAP and RNAPα alone have footprints of 7 and 25 nt [PUB_0728]. We conclude that spx alone has a footprint of 25 nt [PUB_0728]. Regulation Activated by thiol stress [PUB_0434, PUB_0435, PUB_0436]. | |
References |
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Metadata | ||
Created | 2012-10-01 15:07:49 | |
Last updated | 2012-10-01 15:14:28 |