MG_105_OCTAMER – putative DNA integrity scanning protein

Name
WID	MG_105_OCTAMER
Name	putative DNA integrity scanning protein

Structure
Biosynthesis	[c]: (8) MG_105_MONOMER ⇒ MG_105_OCTAMER
No. subunits	8
DNA footprint	Length: 35 (nt), Binding: ssDNA, Region: xsDNA
Empirical formula (pH 7.5)	H₁₃₃₉₂C₈₃₅₂N₂₁₂₈O₂₃₂₈S₁₆
Molecular weight (pH 7.5; Da)	181377.06
Extinction coefficient (260 nm, 25C, pH 7.0)	-139360.00
Half life (OD (600 nm) = 0.3, M9 media, 36C; min)	1200.00

Synthesis
Formation process	Process_MacromolecularComplexation
Localization	c

Function
Enzyme	diadenylate cyclase [c]: (2) ATP ⇒ c_di_AMP + (2) PPI
Reaction participant	DNA bound protein release (putative DNA integrity scanning protein releases Chromosome Segregation Protein SMC with SCP Proteins-ADP) MG_105_OCTAMER[c] + MG_213_214_298_6MER_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_213_214_298_6MER_ADP[c] DNA bound protein release (Holliday junction DNA helicase releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_358_359_10MER[c] ⇒ MG_105_OCTAMER[c] + MG_358_359_10MER[d] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 4mer-(3)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_4MER_3ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_4MER_3ATP_ADP[c] DNA bound protein release (DNA incision complex releases putative DNA integrity scanning protein) MG_073_206_421_TETRAMER[c] + MG_105_OCTAMER[d] ⇒ MG_073_206_421_TETRAMER[d] + MG_105_OCTAMER[c] DNA bound protein release (putative DNA integrity scanning protein releases single-strand binding protein family, octamer) MG_091_OCTAMER[d] + MG_105_OCTAMER[c] ⇒ MG_091_OCTAMER[c] + MG_105_OCTAMER[d] ... 36 more DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 2mer) MG_105_OCTAMER[c] + MG_469_2MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_2MER_ATP[c] DNA bound protein release (formamidopyrimidine-DNA glycosylase releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_498_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_498_MONOMER[d] DNA bound protein release (polI-like 5'-3' exonuclease, putative releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_262_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_262_MONOMER[d] DNA bound protein release (Holliday junction endonuclease releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_352_DIMER[c] ⇒ MG_105_OCTAMER[c] + MG_352_DIMER[d] DNA bound protein release (putative DNA integrity scanning protein releases DNA ligase, NAD-dependent) MG_105_OCTAMER[c] + MG_254_MONOMER[d] ⇒ MG_105_OCTAMER[d] + MG_254_MONOMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 2mer-(1)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_2MER_1ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_2MER_1ATP_ADP[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 7mer-(6)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_7MER_6ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_7MER_6ATP_ADP[c] DNA bound protein release (apurinic endonuclease releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_235_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_235_MONOMER[d] DNA bound protein release (adenine-specific DNA modification methylase releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_184_DIMER[c] ⇒ MG_105_OCTAMER[c] + MG_184_DIMER[d] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 6mer-(5)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_6MER_5ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_6MER_5ATP_ADP[c] DNA bound protein release (putative DNA integrity scanning protein releases adenine-specific DNA modification methylase) MG_105_OCTAMER[c] + MG_184_DIMER[d] ⇒ MG_105_OCTAMER[d] + MG_184_DIMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 3mer) MG_105_OCTAMER[c] + MG_469_3MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_3MER_ATP[c] DNA bound protein release (putative DNA integrity scanning protein releases Spx subfamily protein) MG_105_OCTAMER[c] + MG_127_MONOMER[d] ⇒ MG_105_OCTAMER[d] + MG_127_MONOMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DNA-directed RNA polymerase) MG_105_OCTAMER[c] + RNA_POLYMERASE[d] ⇒ MG_105_OCTAMER[d] + RNA_POLYMERASE[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 5mer) MG_105_OCTAMER[c] + MG_469_5MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_5MER_ATP[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 4mer) MG_105_OCTAMER[c] + MG_469_4MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_4MER_ATP[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ADP) MG_105_OCTAMER[c] + MG_469_1MER_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_1MER_ADP[c] DNA bound protein release (recombination protein, strand exchange releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_339_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_339_MONOMER[d] DNA bound protein release (putative DNA integrity scanning protein releases ferric uptake repressor) MG_105_OCTAMER[c] + MG_236_MONOMER[d] ⇒ MG_105_OCTAMER[d] + MG_236_MONOMER[c] DNA bound protein release (putative DNA integrity scanning protein releases topoisomerase IV) MG_105_OCTAMER[c] + MG_203_204_TETRAMER[d] ⇒ MG_105_OCTAMER[d] + MG_203_204_TETRAMER[c] DNA bound protein release (type I restriction modification DNA specificity domain protein releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_438_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_438_MONOMER[d] DNA bound protein release (putative DNA integrity scanning protein releases Uncharacterized HTH-type transcriptional regulator) MG_101_MONOMER[d] + MG_105_OCTAMER[c] ⇒ MG_101_MONOMER[c] + MG_105_OCTAMER[d] DNA bound protein release (DNA polymerase III, beta subunit releases putative DNA integrity scanning protein) MG_001_MONOMER[c] + MG_105_OCTAMER[d] ⇒ MG_001_MONOMER[d] + MG_105_OCTAMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 3mer-(2)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_3MER_2ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_3MER_2ATP_ADP[c] DNA bound protein release (DNA ligase, NAD-dependent releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_254_MONOMER[c] ⇒ MG_105_OCTAMER[c] + MG_254_MONOMER[d] DNA bound protein release (putative DNA integrity scanning protein releases DNA-directed RNA polymerase holoenzyme) MG_105_OCTAMER[c] + RNA_POLYMERASE_HOLOENZYME[d] ⇒ MG_105_OCTAMER[d] + RNA_POLYMERASE_HOLOENZYME[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 6mer) MG_105_OCTAMER[c] + MG_469_6MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_6MER_ATP[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA 5mer-(4)ATP-(1)ADP) MG_105_OCTAMER[c] + MG_469_5MER_4ATP_ADP[d] ⇒ MG_105_OCTAMER[d] + MG_469_5MER_4ATP_ADP[c] DNA bound protein release (uracil-DNA glycosylase, putative releases putative DNA integrity scanning protein) MG_097_MONOMER[c] + MG_105_OCTAMER[d] ⇒ MG_097_MONOMER[d] + MG_105_OCTAMER[c] DNA bound protein release (putative DNA integrity scanning protein releases type I restriction modification DNA specificity domain protein) MG_105_OCTAMER[c] + MG_438_MONOMER[d] ⇒ MG_105_OCTAMER[d] + MG_438_MONOMER[c] DNA bound protein release (putative DNA integrity scanning protein releases LuxR bacterial regulatory protein, putative) MG_105_OCTAMER[c] + MG_428_DIMER[d] ⇒ MG_105_OCTAMER[d] + MG_428_DIMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP) MG_105_OCTAMER[c] + MG_469_1MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_1MER_ATP[c] DNA bound protein release (putative DNA integrity scanning protein releases DNA topoisomerase I) MG_105_OCTAMER[c] + MG_122_MONOMER[d] ⇒ MG_105_OCTAMER[d] + MG_122_MONOMER[c] DNA bound protein release (putative DNA integrity scanning protein releases heat-inducible transcription repressor HrcA, putative) MG_105_OCTAMER[c] + MG_205_DIMER[d] ⇒ MG_105_OCTAMER[d] + MG_205_DIMER[c] DNA bound protein release (putative DNA integrity scanning protein releases DnaA-ATP 7mer) MG_105_OCTAMER[c] + MG_469_7MER_ATP[d] ⇒ MG_105_OCTAMER[d] + MG_469_7MER_ATP[c] DNA bound protein release (3-5' helicase releases putative DNA integrity scanning protein) MG_105_OCTAMER[d] + MG_244_DIMER[c] ⇒ MG_105_OCTAMER[c] + MG_244_DIMER[d]
Complex subunit	putative DNA integrity scanning protein [c]: (8) MG_105_MONOMER ⇒ MG_105_OCTAMER

Comments
Comments	Composition [PUB_0110]. DNA-binding The DNA footprint of DNA integrity scanning protein DisA has not been experimentally determined. We estimated the DNA footprint of DisA by 1) regressing observed DNA footprint sizes on protein molecular weights, and 2) using this predictor with the calculated DisA molecular weight. This method calculates a 35 nt DisA DNA footprint.
References	Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 31, 474-7 (2003). WholeCell: PUB_0110, PubMed: 12520055, URL: http://www.ncbi.nlm.nih.gov/Structure/

Metadata
Created	2012-10-01 15:07:37
Last updated	2012-10-01 15:14:05