MG_104_MONOMER – ribonuclease R

Name
WID MG_104_MONOMER View in model
Name ribonuclease R View in model
 
Genetics
Gene MG_104 View in model
 
Structure
Sequence
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
MKVLTELQKQIFTIVKKENGKPIPPGIVVRMMENSPNFPGKHLIYRAIDD
LLDWAILRKAGGVTNQLLVNYEPAEPLLDKKLQGILTLGNKNSGFIRSLD
DDKTVYYVHYSNLTGALDGDLVEFCKLDKPQFGDKFDAAVITILKRARIL
YAGNFLVDQNEFALEYKIVADNPRFYLTMIVNPDSIPNNLASNTKIAFQI
DEYDPDNNLCKVSVQQVLGNNDDPLINIKAIMLDNSIVFETNDVVEQHAN
KLSFDTEEQHKAYRQDLTDLAFVTVDPTTSKDLDDAIYVKTIPTGFVLYV
AIADVAHYVNRNSEIDIEAKHKTSSIYLPGHYVVPMLPEQLSNQLCSLNP
AQKRYVVVCEISFDNQGRIKTNKLYPATIISKNRFSYDQVNKWLNNKSEL
NCDETVINSLKAAFTLSDLIQAQRQKRGTIDLSHKETEIVVDEHYFPIKI
NFLVHDKAETMIENLMVVANETVAWVLTNNKIALPYRVHPRPSKKKLQSL
IETVGELNITKPQFNLDTVTSSQIASWLNENKDNPSYEIFVILLLRTLGK
AFYSVNPLMHFSIGSNHYTHFTSPIRRYIDLTIHRLLWMHLFTPDQFTDN
ERDQLKQELEKIADTVNDTEIKIINCERNANDYLTTLLLSKQIGKTFSGF
ISAITSFGIFMRMDENNFDGLIKITTIPDDFFIFEKEKMVLKGRKTNKVY
KIGDRLEAKLSEIDFIQKRAILTLI*
50
100
150
200
250
300
350
400
450
500
550
600
650
700
726
 View in model
Is N‑terminal methionine cleaved
No
 View in model
Empirical formula (pH 7.5) H5901C3744N980O1103S19
Molecular weight (pH 7.5; Da) 82898.82 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)		 66990
Instability index 32.02
Is stable True
Aliphatic index 99.61
GRAVY (25C, pH 7.0) -0.244
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)		 1200 View in model
 
Synthesis
Localization c View in model
Chaperones MG_392_393_21MER View in model
 
Function
Enzyme View in model
 
Parameters
Parameters Parameter_0128: ribonucleaseRFragmentLength = 5 nt View in model
 
Comments
Comments Hydrolytically cleaves RNAs into 2-5 nucleotide fragments in an energy-dependent, exoribonucleolytic fashion [PUB_0039]. Generally responsible for mRNA degradation [PUB_0039]. Functional Macromolecule Functional as monomer [PUB_0096].
References

  1. Nicholson AW. Function, mechanism and regulation of bacterial ribonucleases. FEMS Microbiol Rev 23, 371-90 (1999). WholeCell: PUB_0039, PubMed: 10371039

  2. UniProt Consortium. The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res 37, D169-74 (2009). WholeCell: PUB_0096, PubMed: 18836194, URL: http://www.uniprot.org/uniprot/
 
Metadata
Created 2012-10-01 15:07:48
Last updated 2012-10-01 15:14:27