MG_009_MONOMER – deoxyribonuclease

Name
WID	MG_009_MONOMER
Name	deoxyribonuclease
Cross references	PDB: 1YIX

Genetics
Gene	MG_009

Structure
Sequence	1 51 101 151 201 251 MEYFDAHCHLNCEPLLSEIEKSIANFKLINLKANVVGTDLDNSKIAVELA KKYPDLLKATIGIHPNDVHLVDFKKTKKQLNELLINNRNFISCIGEYGFD YHYTTEFIELQNKFFEMQFEIAETNKLVHMLHIRDAHEKIYEILTRLKPT QPVIFHCFSQDINIAKKLLSLKDLNIDIFFSIPGIVTFKNAQALHEALKI IPSELLLSETDSPWLTPSPFRGKVNWPEYVVHTVSTVAEIKKIEIAEMKR IIVKNAKKLFWH* 50 100 150 200 250 263
Is N‑terminal methionine cleaved	No
Prosthetic groups	(None) MG [c]
Empirical formula (pH 7.5)	H₂₁₉₁C₁₄₀₀N₃₅₄O₃₈₄S₈
Molecular weight (pH 7.5; Da)	30381.95
Extinction coefficient (260 nm, 25C, pH 7.0)	27430
Instability index	35.18
Is stable	True
Aliphatic index	105.67
GRAVY (25C, pH 7.0)	-0.108
Half life (OD (600 nm) = 0.3, M9 media, 36C; min)	1200

Synthesis
Localization	c
Chaperones	MG_392_393_21MER

Function
Enzyme	deoxyribonuclease (dAMP) [c]: dApdAp + H2O ⇒ (2) DAMP + H deoxyribonuclease (dCMP) [c]: dCpdCp + H2O ⇒ (2) DCMP + H deoxyribonuclease (dGMP) [c]: dGpdGp + H2O ⇒ (2) DGMP + H deoxyribonuclease (dTMP) [c]: dTpdTp + H2O ⇒ (2) DTMP + H

Comments
Comments	Functional Macromolecule Functional as monomer [PUB_0096]. Coenzymes Monomer interacts with MG with unknown stoichiometry as prosthetic group [110].
References	UniProt Consortium. The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res 37, D169-74 (2009). WholeCell: PUB_0096, PubMed: 18836194, URL: http://www.uniprot.org/uniprot/

Metadata
Created	2012-10-01 15:07:43
Last updated	2012-10-01 15:14:20