MET – L-Methionine

Name
WID	MET
Name	L-Methionine
Traditional name	methionine
IUPAC name	2-amino-4-(methylsulfanyl)butanoic acid
Cross references	ChEBI: 16643, PubChem: 3373, CAS: 63-68-3, ThreeDMET: B01148, KNApSAcK: C00001379, ... 4 more

Classification
Type	amino_acid

Structure
Empirical formula (pH 7.5)	H₁₁C₅N₁O₂S₁
SMILES (pH 7.5)	C(=O)(O)C(N)CCSC
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	149.21
van der Waals volume (pH 7.5; Å³ molecule^‑1)	137.76
Δ_fG^'o (pH 7.5, 25C, I = 0; kJ mol^‑1)	157.00
pI	6.01
logP	-2.33
logD (pH 7.5)	-2.33

Concentrations
Biomass composition (SP4 media, 5% CO₂, 37C; mmol gDCW^‑1)	0.111472 [c]

Function
Reaction participant	methionine adenosyltransferase [c]: ATP + H2O + MET ⇒ AMET + PI + PPI L-methionine-R-sulfoxide reductase [c]: H2O + MET + MG_124_MONOMER_ox ⇔ METSOXRL + MG_124_MONOMER N-terminal methionine cleavage [c]: H2O + MetMet ⇒ (2) MET methionine synthase [c]: HCYS + MTHF ⇒ H + MET + THF L-methionine-S-sulfoxide reductase [c]: H2O + MET + MG_124_MONOMER_ox ⇔ METSOXSL + MG_124_MONOMER ... 10 more Dipeptide import (Met-Met) [c]: H2O + MetMet ⇒ (2) MET Peptidyl-tRNA hydrolysis (MET) [c]: AMP_MET + H2O ⇒ AMP + MET Protein polymerization (Met) [c]: (2) MET ⇒ H2O + MetMet methionyl-tRNA (MG485) aminoacylation [c]: ATP + MET ⇒ AMP + PPI formyl-methionyl-tRNA (MG488) aminoacylation [c]: ATP + MET ⇒ AMP + PPI homocysteine S-methyltransferase [c]: AMET + HCYS ⇒ AHCYS + H + MET methionyl-tRNA (MG488) formyltransferase [c]: FTHF10 + MET ⇒ FMET + THF Protein degradation (MET) [c]: ATP + (2) H2O + MetMet ⇒ ADP + H + (2) MET + PI Protein degradation (MET) [c]: ATP + (2) H2O + MetMet ⇒ ADP + H + (2) MET + PI formylmethionine hydrolysis [c]: FMET + H2O ⇔ FOR + H + MET

Metadata
Created	2012-10-01 15:07:03
Last updated	2012-10-01 15:12:21