Hpt2 – guanine phosphoribosyltransferase

Name
WID Hpt2 View in model
Name guanine phosphoribosyltransferase View in model
Cross references EC: 2.4.2.8, SABIO-RK: 4291, BioCyc: GUANPRIBOSYLTRAN-RXN, BiGG: GUAPRT, KEGG: R01229
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: GN + PRPP ⇒ GMP + PPI View in model
 
Catalysis
Enzyme MG_458_TETRAMER [c] View in model
Optimal pH
8.4 (dimensionless)
Optimal temperature
37.0 (C)
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) -3.30
Keq
240.127995168 ()
 
Kinetics
Forward kinetics
v = Vmax * [GN] * [PRPP] / (Km1 * Km2 + Km1 * [PRPP] + Km2 * [GN]); Km1 = 3.2 (nM), Km2 = 112 (nM), Vmax = 489.6 1/min (Show evidence)
 View in model
 
Associations
Pathways NUCLEOTIDE_SALVAGE_PWY
Process Process_Metabolism View in model
 
Comments
References

  1. Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/
 
Metadata
Created 2012-10-01 15:08:38
Last updated 2012-10-01 15:16:44