Hpt1 – hypoxanthine phosphoribosyltransferase (Hypoxanthine)
| Name | ||
|---|---|---|
| WID | Hpt1 |
|
| Name | hypoxanthine phosphoribosyltransferase (Hypoxanthine) |
|
| Cross references | EC: 2.4.2.8, SABIO-RK: 4285, BiGG: HXPRT, BioCyc: HYPOXANPRIBOSYLTRAN-RXN, KEGG: R01132 | |
| Classification | ||
| Type | chemical |
|
| Reaction | ||
| Stoichiometry | [c]: HYXN + PRPP ⇒ IMP + PPI |
|
| Catalysis | ||
| Enzyme | MG_458_TETRAMER [c] |
|
| Optimal pH | 8.4 (dimensionless) |
|
| Optimal temperature | 37.0 (C) |
|
| Energetics | ||
| Is spontaneous (pH 7.5, 25C, I = 0) | False |
|
| ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) | -3.30 | |
| Keq | 240.127995168 () |
|
| Kinetics | ||
| Forward kinetics | v = Vmax * [HYXN] * [PRPP] / (Km1 * Km2 + Km1 * [PRPP] + Km2 * [HYXN]); Km1 = 2.7 (nM), Km2 = 138 (nM), Vmax = 954.0 1/min |
|
| Associations | ||
| Pathways | NUCLEOTIDE_SALVAGE_PWY | |
| Process | Process_Metabolism |
|
| Metadata | ||
| Created | 2012-10-01 15:08:38 | |
| Last updated | 2012-10-01 15:16:43 | |
