HYXN – hypoxanthine

Name
WID	HYXN
Name	hypoxanthine
Traditional name	hypoxanthine
IUPAC name	6,7-dihydro-1H-purin-6-one
Cross references	ChEBI: 17368, PubChem: 3560, CAS: 68-94-0, ThreeDMET: B00078, KNApSAcK: C00001502, ... 4 more

Classification
Type	modified_nucleobase

Structure
Empirical formula (pH 7.5)	H₄C₅N₄O₁
SMILES (pH 7.5)	O=C1NC=NC2=C1NC=N2
Charge (pH 7.5)	0
Is hydrophobic	False
Molecular weight (Da)	136.11
van der Waals volume (pH 7.5; Å³ molecule^‑1)	103.76
Δ_fG^'o (pH 7.5, 25C, I = 0; kJ mol^‑1)	268.90
pI	4.40
logP	-0.880
logD (pH 7.5)	-0.890

Concentrations
Media composition (SP4; mM)	0.00726

Function
Reaction participant	hypoxanthine phosphoribosyltransferase (Hypoxanthine) [c]: HYXN + PRPP ⇒ IMP + PPI purine-nucleoside phosphorylase (Inosine) [c]: HYXN + R1P ⇔ (2) H + INS + PI Spontaneous base deamination (adenine ==> hypoxanthine) [c]: AD + H2O ⇒ HYXN + NH3 DNA radiation (gamma-ray) induced base oxidation (hypoxanthine ==> xanthine; hydroxyl radical) gamma_radiation[e] + hydroxyl_radical[c] + HYXN[c] ⇒ H[c] + XAN[c] adenine deaminase [c]: AD + H2O ⇒ HYXN + NH3 purine-nucleoside phosphorylase (Deoxyinosine) [c]: dINS + PI ⇔ DR1P + HYXN

Metadata
Created	2012-10-01 15:07:01
Last updated	2012-10-01 15:12:17