Gmk1 – guanylate kinase (GMP:ATP)

Name
WID	Gmk1
Name	guanylate kinase (GMP:ATP)
Cross references	EC: 2.7.4.8, BiGG: GK1, BioCyc: GUANYL-KIN-RXN, KEGG: R00332

Classification
Type	chemical

Reaction
Stoichiometry	[c]: ATP + GMP ⇔ ADP + GDP

Catalysis
Enzyme	MG_107_DIMER [c]
Optimal pH	7.6 (dimensionless)
Optimal temperature	31.0 (C)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	0.0
K_eq	1.0 ()

Kinetics
Forward kinetics	v = V_max * [GMP] / (K_m + [GMP]); K_m = 41 (nM), V_max = 1581.0 U/mg (Show evidence) Value: Rate law: VmaxGMP/(Km+GMP); Km = 0.041 mM, Vmax = 1581 umol/(minmg) (None) Measured: Yes Species: Saccharomyces cerevisiae References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	NUCLEOTIDE_SALVAGE_PWY
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:08:37
Last updated	2012-10-01 15:16:40