GapA – glyceraldehyde-3-phosphate dehydrogenase

Name
WID GapA View in model
Name glyceraldehyde-3-phosphate dehydrogenase View in model
Cross references EC: 1.2.1.12, SABIO-RK: 3429, BiGG: GAPD, BioCyc: GAPOXNPHOSPHN-RXN, KEGG: R01061
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: NAD + PI + T3P1 ⇔ DPG + H + NADH View in model
 
Catalysis
Enzyme MG_301_TETRAMER [c] View in model
Optimal pH
8.5 (dimensionless)
Optimal temperature
30.0 (C)
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) -0.300
Keq
1.64590173173 ()
 
Kinetics
Forward kinetics
v = Vmax * [T3P1] * [NAD] / ((1 + Km2) * [T3P1] + Km1 * [NAD]); Km1 = 90 (nM), Km2 = 39 (nM), Vmax = 225.0 U/mg (Show evidence)
 View in model
Backward kinetics
v = Vmax * [DPG] * [NADH] / ((1 + Km2) * [DPG] + Km1 * [NADH]); Vmax = 204.0 U/mg (Show evidence)
 View in model
 
Associations
Pathways GLYCOLYSIS
Process Process_Metabolism View in model
 
Comments
References

  1. Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/
 
Metadata
Created 2012-10-01 15:08:35
Last updated 2012-10-01 15:16:33