DNADamage_THY_O4mTHY_MNNG – DNA base methylation (thymine ==> 4'-O-methylthymine; N-methyl-N'-nitro-N-nitrosoguanidine)
Name | ||
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WID | DNADamage_THY_O4mTHY_MNNG |
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Name | DNA base methylation (thymine ==> 4'-O-methylthymine; N-methyl-N'-nitro-N-nitrosoguanidine) |
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Classification | ||
Type | base_methylation |
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Reaction | ||
Stoichiometry | [c]: MNNG + THY ⇒ NNG + O4mTHY |
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Energetics | ||
Is spontaneous (pH 7.5, 25C, I = 0) | True |
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Associations | ||
Process | Process_DNADamage |
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Comments | ||
Comments | methylated predominantly in ssDNA by SN2 agents (eg. MMS), 10% of DNA methylation [PUB_0465]; relative rate: 0% MNNG methylations [PUB_0467] | |
References |
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Metadata | ||
Created | 2012-10-01 15:08:32 | |
Last updated | 2012-10-01 15:16:25 |