DNADamage_GammaRadiationInducedStrandBreak – Radiation (gamma-ray) induced strand break

Name
WID DNADamage_GammaRadiationInducedStrandBreak View in model
Name Radiation (gamma-ray) induced strand break View in model
 
Classification
Type strand_break View in model
 
Reaction
Stoichiometry dRibose5P_dRibose5P[c] + gamma_radiation[e] + H2O[c] ⇒ (2) DR5P[c] + H[c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) True View in model
 
Associations
Process Process_DNADamage View in model
 
Comments
Comments Calculated from 1) total gamma ray single and double strand break yields 5.6e-10 and 1.6e-12 1/Gy/DA [PUB_0497], and 2) 305 DA/nt.
References

  1. Gulston M, Fulford J, Jenner T, de Lara C, O'Neill P. Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites. Nucleic Acids Res 30, 3464-72 (2002). WholeCell: PUB_0497, PubMed: 12140332
 
Metadata
Created 2012-10-01 15:08:30
Last updated 2012-10-01 15:16:18