DNADamage_GN_m8GN_CH3 – DNA base methylation (guanine ==> 8-methylguanine; Methyl radical)

Name
WID DNADamage_GN_m8GN_CH3 View in model
Name DNA base methylation (guanine ==> 8-methylguanine; Methyl radical) View in model
 
Classification
Type base_methylation View in model
 
Reaction
Stoichiometry [c]: CH3 + GN + H ⇒ m8GN View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) True View in model
 
Associations
Process Process_DNADamage View in model
 
Comments
Comments methylated by most agents (eg. SN1 agents such as MNNG, MNU or SN2 agents such as MMS, DMS), 70% of DNA methylation [PUB_0465]
References

  1. Sedgwick B. Repairing DNA-methylation damage. Nat Rev Mol Cell Biol 5, 148-57 (2004). WholeCell: PUB_0465, PubMed: 15040447
 
Metadata
Created 2012-10-01 15:08:31
Last updated 2012-10-01 15:16:21