DNADamage_GN_m7GN_MNNG – DNA base methylation (guanine ==> 7-methylguanine; N-methyl-N'-nitro-N-nitrosoguanidine)

Name
WID DNADamage_GN_m7GN_MNNG View in model
Name DNA base methylation (guanine ==> 7-methylguanine; N-methyl-N'-nitro-N-nitrosoguanidine) View in model
 
Classification
Type base_methylation View in model
 
Reaction
Stoichiometry [c]: GN + H + MNNG ⇒ m7GN + NNG View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) True View in model
 
Associations
Process Process_DNADamage View in model
 
Comments
Comments relative rate: 67% MNNG methylations [PUB_0467]
References

  1. Beranek DT. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat Res 231, 11-30 (1990). WholeCell: PUB_0467, PubMed: 2195323
 
Metadata
Created 2012-10-01 15:08:31
Last updated 2012-10-01 15:16:21